Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	1700049E17Rik2tm1(KOMP)Mbp
Name:	tandem duplication of RIKEN cDNA 1700049E17 gene, gene 2; targeted mutation 1, Mouse Biology Program, UC Davis
MGI ID:	MGI:5293869
Gene:	1700049E17Rik2  Location: Chr14:41295168-41303262 bp, + strand  Genetic Position: Chr14, 22.38 cM
IMPC:	1700049E17Rik2 gene page

Mutant Cell Lines:	DEPD00571_3_A04, DEPD00571_3_D03, DEPD00571_3_D04, DEPD00571_3_E04, DEPD00571_3_F03, DEPD00571_3_G02, DEPD00571_3_G03, DEPD00571_3_G04
Germline Transmission:	Unknown
Parent Cell Line:	JM8A3.N1 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P   Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 762 starting at position 41295559 and ending at position 41296321 of Chromosome 14 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157064)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any 1700049E17Rik2 Mutation:	1 strain or line available

Original:	J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010;
All:	1 reference(s)