Summary | Transgene origin | Transgene description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(CAG-mRFP1,-SOX9,-EGFP)1Haak
Name:	transgene insertion 1, Haruhiko Akiyama
MGI ID:	MGI:5293615
Synonyms:	CAG-mRFP1floxed-Sox9-EGFP, CAG-Sox9
Transgene:	Tg(CAG-mRFP1,-SOX9,-EGFP)1Haak  Location: unknown
Alliance:	Tg(CAG-mRFP1,-SOX9,-EGFP)1Haak page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(CAG-mRFP1,-SOX9,-EGFP)1Haak expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Sox9 (MGI:98371)   Mutation details: The transgene consists of the CAG promoter, a cassette containing a loxP-flanked mRFP1 gene and 4 tandem polyadneylation sites, the human SOX9 cDNA with a 3x hemagglutinin epitope tag, and an IRES-EGFP-polyA sequence. The vector was injected into C57BL/6 oocytes to generated mice. 8 founders were obtained and one line that showed significant levels of (ubiquitous) mRFP1 expression was chosen for further study. (J:176952)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:176952 Kim Y, et al., Generation of transgenic mice for conditional overexpression of Sox9. J Bone Miner Metab. 2011 Jan;29(1):123-9
All:	10 reference(s)