Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gprc5ctm1Yhir
Name:	G protein-coupled receptor, family C, group 5, member C; targeted mutation 1, Yoshio Hirabayashi
MGI ID:	MGI:5293388
Gene:	Gprc5c  Location: Chr11:114741978-114763443 bp, + strand  Genetic Position: Chr11, 80.54 cM
Alliance:	Gprc5ctm1Yhir page

Germline Transmission:	Earliest citation of germline transmission: J:176063
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 was replaced with lacZ and neo cassettes via homologous recombination. LacZ expression recapitulates endogenous gene expression. (J:176063)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gprc5c Mutation:	60 strains or lines available

Original:	J:176063 Sano T, et al., Comparative characterization of GPRC5B and GPRC5CLacZ knockin mice; behavioral abnormalities in GPRC5B-deficient mice. Biochem Biophys Res Commun. 2011 Sep 2;412(3):460-5
All:	3 reference(s)