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Tg(Alx4-cre/ERT2)1Bky
Transgene Detail
Summary
Symbol: Tg(Alx4-cre/ERT2)1Bky
Name: transgene insertion 1, Bradley K Yoder
MGI ID: MGI:5291907
Synonyms: Alx4-CreERT2, Gardener Mouse, Tg(Alx4-cre/ERT2)GRD1Bky
Transgene: Tg(Alx4-cre/ERT2)1Bky  Location: unknown  
Alliance: Tg(Alx4-cre/ERT2)1Bky page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Alx4-cre/ERT2)1Bky expression driven by 1 gene
 
Mutation detailsA 17kb promoter fragment of the mouse Alx4 (aristaless-like homeobox 4) was cloned upstream of the CreERT2 cDNA fusing Cre at codon 13 located within exon 2. This linear fragment was injected into pronuclei and chimeras were generated. The site of integration is unknown. (J:328710)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Alx4 (mouse)
Summary of all recombinase alleles driven by Alx4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:328710 Rockwell DM, et al., A transgenic Alx4-CreER mouse to analyze anterior limb and nephric duct development. Dev Dyn. 2022 Sep;251(9):1524-1534
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory