Summary | Mutation origin | Mutation description | Find Mice (IMSR) | Notes | References

Symbol:	Gt(ROSA)26Sortm4Mgn
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Mark A Magnuson
MGI ID:	MGI:5287870
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm4Mgn page

Germline Transmission:	Earliest citation of germline transmission: J:174255
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (RMCE-ready, Reporter) Mutation:    Insertion   Mutation details: Recombinase mediated cassette exchange (RMCE) replaced the selection cassettes in Gt(ROSA)26Sortm1Mgn with the 5'UTR Xenopus beta-globin translation enchancer, citrine fluorescent protein (YFP), beta-globin intron, polyadenylation sequence, and an FRT-flanked neo cassette. (J:174255)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:174255 Chen SX, et al., Quantification of factors influencing fluorescent protein expression using RMCE to generate an allelic series in the ROSA26 locus in mice. Dis Model Mech. 2011 Jul-Aug;4(4):537-47
All:	1 reference(s)