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Gene Expression Data
Assay Details
Assay
Reference: J:142123 Ishimura A, et al., Man1, an inner nuclear membrane protein, regulates left-right axis formation by controlling nodal signaling in a node-independent manner. Dev Dyn. 2008 Dec;237(12):3565-76
Assay type: RNA in situ
MGI Accession ID: MGI:5287262
Gene symbol: Pitx2
Gene name: paired-like homeodomain transcription factor 2
Probe: Pitx2 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen Table 1 1s wild type: embryonic day 8.0 (more )
Note: 1 somite stage.
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Absent
Specimen Table 1 1s Man1 mutant: embryonic day 8.0; Lemd3Gt(XST167)Byg/Lemd3Gt(XST167)Byg (more )
Note: 1 somite stage.
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Absent
Specimen Table 1 2s wild type: embryonic day 8.0 (more )
Note: 2 somite stage.
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Absent
Specimen Table 1 2s Man1 mutant: embryonic day 8.0; Lemd3Gt(XST167)Byg/Lemd3Gt(XST167)Byg (more )
Note: 2 somite stage.
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present Regionally restricted Ectopic bilateral expression was detected by the 2 somite stage.
Specimen 3K: embryonic day 8.0 (more )
Note: 3 somite stage.
Structure Level Pattern Image Note
TS12: head mesenchyme Present Regionally restricted 3K Bilateral expression was detected.
TS12: lateral plate mesoderm Present Regionally restricted 3K Expression was detected in the left lateral plate mesoderm.
Specimen 3L: embryonic day 8.0; Lemd3Gt(XST167)Byg/Lemd3Gt(XST167)Byg (more )
Note: 3 somite stage.
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present Regionally restricted 3L Intense expression was detected on both sides of the lateral plate mesoderm. In 3 of 7 embryos this expression was continuous, whereas others showed discrete anterior and posterior domains. The right posterior expression was weaker than the left.
Specimen 3M: embryonic day 8.5 (more )
Note: 8-10 somite stage.
Structure Level Pattern Image Note
TS13: head mesenchyme Present Regionally restricted 3M Bilateral expression in the head mesenchyme was detected.
TS13: lateral plate mesoderm Present Regionally restricted 3M Expression extends laterally along the anteroposterior axis in the left lateral plate mesoderm.
Specimen 3N: embryonic day 8.5; Lemd3Gt(XST167)Byg/Lemd3Gt(XST167)Byg (more )
Note: 8-10 somite stage.
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present Regionally restricted 3N Intense expression was detected on both sides of the lateral plate mesoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory