Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:58474
Arango NA, et al., Targeted mutagenesis of the endogenous mouse Mis gene promoter: in vivo definition of genetic pathways of vertebrate sexual development. Cell. 1999 Nov 12;99(4):409-19
|
|
Assay type:
|
In situ reporter (knock in)
|
|
MGI Accession ID:
|
MGI:5286067
|
|
Gene symbol:
|
Amhr2
|
|
Gene name:
|
anti-Mullerian hormone type 2 receptor
|
|
Reporter:
|
lacZ
|
|
|
Direct Detection
|
|
|
Results
|
Specimen
+/+;MRKI/+ female:
postnatal; Amhr2tm2Bhr/Amhr2 +
(more )
Specimen
+/+;MRKI/+ female:
(close )
|
Genetic Background:
|
involves: 129S7/SvEvBrd
|
|
Mutant Allele(s):
|
Amhr2tm2Bhr/Amhr2+
|
|
Age:
|
postnatal
|
|
Sex:
|
Female
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: uterus |
Present |
|
4C +/+;MRKI/+
|
|
Specimen
Not shown:
postnatal; Amhr2tm2Bhr/Amhr2 +
(more )
Specimen
Not shown:
(close )
|
Genetic Background:
|
involves: 129S7/SvEvBrd
|
|
Mutant Allele(s):
|
Amhr2tm2Bhr/Amhr2+
|
|
Age:
|
postnatal
|
|
Sex:
|
Female
|
|
Type:
|
whole mount
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: myometrium |
Present |
|
|
Expression is present in the longitudinal muscle layer of the uterine body and horns.
|
Specimen
+/+; MRKI/MRKI male:
(close )
|
Genetic Background:
|
involves: 129S7/SvEvBrd
|
|
Mutant Allele(s):
|
Amhr2tm2Bhr/Amhr2tm2Bhr
|
|
Age:
|
postnatal
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: uterus |
Present |
|
4C +/+; MRKI/MRKI
|
Expression is present in the presumptive uterine tissue, present due to lack of Mullerian duct regression.
|
Specimen
R1/R1-neo;MRKI/+ male:
(close )
|
Genetic Background:
|
involves: 129S7/SvEvBrd * C57BL/6
|
|
Mutant Allele(s):
|
Amhtm2Bhr/Amhtm2.1Bhr Amhr2tm2Bhr/Amhr2+
|
|
Age:
|
postnatal
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: uterus |
Present |
|
4C R1/R1-neo;MRKI/+
|
Expression is present in the presumptive uterine tissue, present due to lack of Mullerian duct regression.
|
Specimen
Not shown:
(close )
|
Genetic Background:
|
involves: 129S7/SvEvBrd * C57BL/6
|
|
Mutant Allele(s):
|
Amhtm2Bhr/Amhtm2.1Bhr Amhr2tm2Bhr/Amhr2+
|
|
Age:
|
postnatal
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: uterus |
Present |
Regionally restricted |
|
Expression is present in a pattern identical to that seen in females (i.e. in the longitudinal muscle layer of the uterine body and horns).
|
|