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Stc2tm1Gthi
Targeted Allele Detail
Summary
Symbol: Stc2tm1Gthi
Name: stanniocalcin 2; targeted mutation 1, Gopal Thinakaran
MGI ID: MGI:5285561
Gene: Stc2  Location: Chr11:31309441-31320061 bp, - strand  Genetic Position: Chr11, 18.4 cM
Alliance: Stc2tm1Gthi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:175075
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding sequence of exons 1 and 2 were replaced with a lacZ/neo cassette. The absence of transcript expression was confirmed by western blot analysis in kidney extract. (J:175075)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stc2 Mutation:  20 strains or lines available
References
Original:  J:175075 Zeiger W, et al., Stanniocalcin 2 is a negative modulator of store-operated calcium entry. Mol Cell Biol. 2011 Sep;31(18):3710-22
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory