Reporter:	lacZ
	Direct Detection

Structure	Level	Pattern	Image	Note
TS13: future brain neural fold	Present	Regionally restricted	2A	Expression in the anterior margin of the head folds.

Structure	Level	Pattern	Image	Note
TS13: gut endoderm	Present	Regionally restricted	2B	Expression in the endoderm of the foregut portal and prospective hindgut.

Structure	Level	Pattern	Image	Note
TS13: future brain neural fold	Present		2C
TS13: hindgut diverticulum	Present		2C

Structure	Level	Pattern	Image	Note
TS13: foregut diverticulum	Present		2D

Structure	Level	Pattern	Image	Note
TS17: physiological umbilical hernia	Present		2E	Expression in the tissues around umbilical region.
TS17: branchial arch	Present		2E
TS17: forebrain	Present		2E
TS17: heart	Present		2E
TS17: midbrain	Present		2E
TS17: midgut	Present		2E
TS17: septum transversum	Present		2E

Structure	Level	Pattern	Image	Note
TS17: Rathke's pouch	Present		2F
TS17: heart	Present		2F
TS17: septum transversum	Present		2F
TS17: forelimb bud mesenchyme	Present	Regionally restricted	2F	Expression in the mesothelial layer of the dorsal mesentery cells within the proximal region of the limb buds.
TS17: oral region cavity	Present	Regionally restricted	2F	Expression in the ectoderm of the oral cavity.
TS17: body wall mesenchyme	Present	Regionally restricted	2F	Expression in the splanchnic mesoderm in the umbilical region.

Structure	Level	Pattern	Image	Note
TS17: diencephalon	Present	Regionally restricted	2G	Expression in the neuroepithelial floor of the diencephalon.
TS17: midbrain	Present		2G
TS17: optic cup outer layer	Present		2G
TS17: eye mesenchyme	Present	Regionally restricted	2G	Expression in the perioptic mesenchyme.
TS17: nasal process mesenchyme	Present	Regionally restricted	2G	Expression in the nasal mesenchyme.

Structure	Level	Pattern	Image	Note
TS17: neural tube lateral wall	Present	Regionally restricted	2H	Expression in the lateral motor column of the neural tube.
TS17: embryo mesenchyme	Present	Regionally restricted	2H	Expression in the perinotochordal mesoderm adjacent to the dorsal aorta.
TS17: dorsal root ganglion	Present		2H
TS17: myotome	Present		2H
TS17: sclerotome	Present		2H

Structure	Level	Pattern	Image	Note
TS11: embryo	Present	Uniform		Express uniformly in the germ layers.
TS11: extraembryonic component	Present	Uniform

Structure	Level	Pattern	Image	Note
TS15: future forebrain	Present
TS15: heart atrium	Present
TS15: outflow tract	Present
TS15: gut	Present	Regionally restricted		Expression in the gut of the lower trunk.

Structure	Level	Pattern	Image	Note
TS21: hindbrain	Present	Regionally restricted	3A	Expression in the ventral hindbrain.
TS21: gut mesenchyme	Present	Regionally restricted	3A	Expression in the gut mesoderm.
TS21: heart	Present		3A
TS21: hypothalamus	Present		3A
TS21: midbrain roof plate	Present		3A
TS21: pituitary gland	Present		3A
TS21: thalamus	Present		3A
TS21: tongue	Present		3A
TS21: telencephalon	Absent		3A
TS21: liver parenchyma	Absent		3A	Expression is undetectable in the hepatocytes.

Structure	Level	Pattern	Image	Note
TS23: enamel knot	Present		3D , 3B
TS23: diencephalon	Present	Regionally restricted	3B	Expression in the mammillary area.
TS23: cerebellum	Present		3B
TS23: choroid plexus	Present		3B
TS23: hindbrain	Present		3B
TS23: hypothalamus	Present		3B
TS23: main olfactory bulb	Present		3B
TS23: midbrain	Present		3B
TS23: olfactory epithelium	Present		3B
TS23: pituitary gland	Present		3B
TS23: thalamus	Present		3B
TS23: tongue	Present		3B
TS23: tooth	Present		3B
TS23: cerebral cortex	Absent		3B
TS23: vibrissa follicle	Present		3B

Structure	Level	Pattern	Image	Note
TS26: cerebellum	Present	Regionally restricted	3C , 3E	Expression in the developing purkinje cell layer of the cerebellum.
TS26: diencephalon	Present	Regionally restricted	3C	Expression in the mammillary area.
TS26: cerebral cortex	Absent		3C
TS26: hindbrain	Present		3C
TS26: hypothalamus	Present		3C
TS26: main olfactory bulb	Present		3C
TS26: midbrain	Present		3C
TS26: olfactory epithelium	Present		3C
TS26: pituitary gland	Present		3C
TS26: thalamus	Present		3C
TS26: tongue	Present		3C
TS26: tooth	Present		3C
TS26: vibrissa follicle	Present		3C
TS26: choroid plexus	Present		3C , 3E

Structure	Level	Pattern	Image	Note
TS26: upper jaw incisor enamel organ	Present	Regionally restricted	3F	Expression in the ameloblasts and odontoblasts.

Structure	Level	Pattern	Image	Note
TS27: eye	Present	Regionally restricted	3G	Expression in the region of the developing trabecular meshwork.
TS27: sclera	Present	Regionally restricted	3G	Expression in the region of the perioptic mesenchyme.
TS27: ciliary body	Present		3G
TS27: cornea stroma	Present		3G
TS27: iris stroma	Present		3G
TS27: retina ganglion cell layer	Present		3G

Structure	Level	Pattern	Image	Note
TS23: ventricle cardiac muscle	Present	Regionally restricted	3H	Expression in the non-compact region of the ventricular myocardium.
TS23: liver parenchyma	Absent		3H	Expression is undetectable in the hepatocytes.
TS23: thymus primordium	Absent		3H
TS23: heart atrium	Present		3H
TS23: heart valve	Present		3H
TS23: intercostal muscle	Present		3H
TS23: lung	Present		3H

Structure	Level	Pattern	Image	Note
TS23: lung mesenchyme	Present	Regionally restricted	3I	Expression in the prospective smooth muscle surrounding the bronchi.

Structure	Level	Pattern	Image	Note
TS26: esophagus mesenchyme	Present	Regionally restricted	3J	Expression in the smooth muscle layers of the upper oesophagus.

Structure	Level	Pattern	Image	Note
TS27: skeletal muscle	Present	Regionally restricted	3K	Expression in the spindle fibres and newly formed myotubes with centrally located nuclei.

Structure	Level	Pattern	Image	Note
TS27: bone	Present	Regionally restricted	3L	High levels expression in the proliferative zone, perichondrial region and sites of future articular cartilage but is weak or absent in the hypertrophic or ossifying regions.
TS27: articular cartilage	Present		3L
TS27: dorsal root ganglion	Present		3L

Structure	Level	Pattern	Image	Note
TS27: brown fat	Strong	Regionally restricted	3M	Intense staining in the interscapular brown adipose tissue.
TS27: hair follicle	Present		3M

Structure	Level	Pattern	Image	Note
TS25: brown fat	Strong

Structure	Level	Pattern	Image	Note
TS28: liver vascular element	Strong	Regionally restricted		Expression in the endothelium of the hepatic vasculature.
TS28: brown fat	Strong	Regionally restricted		Expression in the interscapular region and in areas around the major vessels of the heart, at the kidney hilus and in small deposits in the head and neck.
TS28: gut	Present	Regionally restricted		Expression in the smooth muscle.
TS28: renal convoluted tubule	Weak	Regionally restricted		Expression in the distal convoluted tubules.
TS28: renal medulla	Weak
TS28: atrium cardiac muscle	Present
TS28: detrusor muscle of bladder	Present
TS28: hair inner root sheath	Present
TS28: hair root sheath matrix	Present
TS28: heart valve	Present
TS28: vibrissa follicle	Present

Structure	Level	Pattern	Image	Note
TS21: liver vascular element	Strong	Regionally restricted		Expression in the endothelium of the hepatic vasculature.

Structure	Level	Pattern	Image	Note
TS23: liver vascular element	Strong	Regionally restricted		Expression in the endothelium of the hepatic vasculature.

Structure	Level	Pattern	Image	Note
TS28: brown fat	Strong		5A
TS28: brainstem	Present	Regionally restricted	5A	Expression in the lateral lemniscus.
TS28: adenohypophysis pars intermedia	Present	Regionally restricted	5D , 5A	Expression is restricted principally to the melanotroph cells of the intermediate lobe.
TS28: cochlea	Present		5A
TS28: piriform cortex	Present		5A
TS28: raphe nucleus	Present		5A
TS28: superior cervical ganglion	Present		5A
TS28: superior colliculus	Present		5A

Structure	Level	Pattern	Image	Note
TS28: brown fat	Strong		5B
TS28: dorsal root ganglion	Present		5B
TS28: spinal cord gray matter	Present		5B

Structure	Level	Pattern	Image	Note
TS28: dorsal root ganglion	Present		5C
TS28: cervical ganglion	Present		5C	Expression in the sympathetic ganglia of the cervical region.

Structure	Level	Pattern	Image	Note
TS28: iris	Present		5E
TS28: retina	Present		5E
TS28: lens fiber	Present	Regionally restricted	5E	Expression in some secondary fibres.
TS28: lens epithelium	Present	Regionally restricted	5E	Expression in some cells of the anterior epithelium.

Structure	Level	Pattern	Image	Note
TS28: retina outer nuclear layer	Strong		5F
TS28: retina ganglion cell layer	Present		5F
TS28: retina inner nuclear layer	Present		5F

Structure	Level	Pattern	Image	Note
TS28: cochlear ganglion	Present		5G

Structure	Level	Pattern	Image	Note
TS28: olfactory epithelium	Strong	Regionally restricted	5H	Expression in the basal layer of the olfactory epithelium.

Structure	Level	Pattern	Image	Note
TS28: ventricle cardiac muscle	Present	Regionally restricted	5I	Expression in cardiomyocytes.

Structure	Cell Type	Level	Pattern	Image	Note
TS28: Sertoli cell	Sertoli cell	Present		5J
TS28: spermatid		Present		5J

Structure	Level	Pattern	Image	Note
TS28: stomach smooth muscle	Present		5K
TS28: enteric ganglion	Present		5K	Ganglion cells within the enteric nervous system of the gut.

Structure	Level	Pattern	Image	Note
TS28: esophagus squamous epithelium	Present	Regionally restricted	5L	Expression in the superficial layers of the stratified squamous epithelium (sl) but not in the stem cell-containing basal layer.
TS28: esophagus smooth muscle	Absent		5L

Structure	Level	Pattern	Image	Note
TS17: Rathke's pouch	Present
TS17: dorsal root ganglion	Present
TS17: heart	Present
TS17: myotome	Present
TS17: sclerotome	Present
TS17: diencephalon	Present	Regionally restricted		Expression in the neuroepithelium of the neurons diffuse.
TS17: hindbrain	Present	Regionally restricted		Expression in the neuroepithelium of the neurons diffuse.
TS17: midbrain	Present	Regionally restricted		Expression in the neuroepithelium of the neurons diffuse.
TS17: neural tube lateral wall	Present			Lateral motor column
TS17: telencephalon	Absent			No expression in the neuroepithelium of the neurons diffuse.

Structure	Cell Type	Level	Pattern	Image	Note
TS23: cartilage		Present
TS23: caudate-putamen		Present
TS23: choroid plexus		Present
TS23: cochlea		Present
TS23: detrusor muscle of bladder		Present
TS23: dorsal root ganglion		Present
TS23: heart		Present
TS23: medullary raphe		Present
TS23: olfactory epithelium		Present
TS23: pituitary gland		Present
TS23: retina		Present
TS23: superior colliculus		Present
TS23: sympathetic ganglion		Present
TS23: tongue muscle		Present
TS23: tooth		Present
TS23: diencephalon		Present	Regionally restricted		Expression in the mammillary area and neurons diffuse.
TS23: gut		Present	Regionally restricted		Expression in the smooth muscle.
TS23: midbrain		Present	Regionally restricted		Expression in the neurons diffuse.
TS23: hindbrain		Present	Regionally restricted		Expression in the neurons diffuse.
TS23: cerebellum		Present	Regionally restricted		Expression in the purkinje neurons.
TS23: spinal cord		Present	Regionally restricted		Expression in neurons within grey matter.
TS23: cerebral cortex		Absent			No expression in the neurons diffuse.
TS23: Sertoli cell	Sertoli cell	Absent
TS23: collecting duct		Absent
TS23: immature loop of Henle		Absent
TS23: hypothalamus		Present	Regionally restricted		Expression in the hypothalamic nuclei.
TS23: thalamus		Present	Regionally restricted		Expression in the thalamic nuclei.
TS23: parasympathetic nervous system		Present	Regionally restricted		Expression in the parasympathetic ganglia.

Structure	Cell Type	Level	Pattern	Image	Note
TS26: cerebral cortex		Absent			No expression in the neurons diffuse.
TS26: piriform cortex		Absent
TS26: main olfactory bulb		Present	Regionally restricted		Expression in the mitral cell layer, but not in the granular cell layer.
TS26: Sertoli cell	Sertoli cell	Absent
TS26: brown fat		Present
TS26: cartilage		Present
TS26: caudate-putamen		Present
TS26: choroid plexus		Present
TS26: cochlea		Present
TS26: collecting duct		Present
TS26: cortical renal tubule		Present
TS26: detrusor muscle of bladder		Present
TS26: dorsal root ganglion		Present
TS26: hair follicle		Present
TS26: heart		Present
TS26: loop of Henle		Present
TS26: medullary raphe		Present
TS26: olfactory epithelium		Present
TS26: pituitary gland		Present
TS26: retina		Present
TS26: superior colliculus		Present
TS26: sympathetic ganglion		Present
TS26: tongue muscle		Present
TS26: tooth		Present
TS26: vibrissa follicle		Present
TS26: diencephalon		Present	Regionally restricted		Expression in the mammillary area and neurons diffuse.
TS26: midbrain		Present	Regionally restricted		Expression in the neurons diffuse.
TS26: hindbrain		Present	Regionally restricted		Expression in the neurons diffuse.
TS26: cerebellum		Present	Regionally restricted		Expression in the purkinje neurons.
TS26: spinal cord		Present	Regionally restricted		Expression in neurons within grey matter.
TS26: gut		Present	Regionally restricted		Expression in the smooth muscle.
TS26: blood vessel		Present	Regionally restricted		Expression in the endothelial cells.
TS26: hypothalamus		Present	Regionally restricted		Expression in the hypothalamic nuclei.
TS26: thalamus		Present	Regionally restricted		Expression in the thalamic nuclei.
TS26: parasympathetic nervous system		Present	Regionally restricted		Expression in the parasympathetic ganglia.

Structure	Cell Type	Level	Pattern	Image	Note
TS28: adenohypophysis pars intermedia		Present
TS28: blood vessel endothelium		Present
TS28: brown fat		Present
TS28: cartilage		Present
TS28: caudate-putamen		Present
TS28: cerebellum Purkinje cell layer		Present
TS28: choroid plexus		Present
TS28: cochlea		Present
TS28: collecting duct		Present
TS28: detrusor muscle of bladder		Present
TS28: distal convoluted tubule		Present
TS28: dorsal root ganglion		Present
TS28: enteric ganglion		Present
TS28: hair follicle		Present
TS28: heart		Present
TS28: hypothalamic nucleus		Present
TS28: loop of Henle of renal medulla		Present
TS28: olfactory epithelium		Present
TS28: parasympathetic ganglion		Present
TS28: piriform cortex		Present
TS28: raphe nucleus		Present
TS28: retina		Present
TS28: spinal cord gray matter		Present
TS28: superior colliculus		Present
TS28: sympathetic ganglion		Present
TS28: thalamic nucleus		Present
TS28: tongue muscle		Present
TS28: vibrissa follicle		Present
TS28: cerebral cortex		Present	Regionally restricted		Expression in the neurons diffuse.
TS28: main olfactory bulb granule cell layer		Present
TS28: main olfactory bulb mitral cell layer		Present
TS28: mammillary body		Present
TS28: diencephalon		Present	Regionally restricted		Expression in the neurons diffuse.
TS28: hindbrain		Present	Regionally restricted		Expression in the neurons diffuse.
TS28: midbrain		Present	Regionally restricted		Expression in the neurons diffuse.
TS28: gut		Present	Regionally restricted		Expression in the smooth muscle.
TS28: Sertoli cell	Sertoli cell	Present
TS28: spermatid		Present	Regionally restricted		Expression in the condensed spermatids.