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Gene Expression Data
Assay Details
Assay
Reference: J:169664 Guyot MC, et al., A novel hypomorphic Looptail allele at the planar cell polarity Vangl2 gene. Dev Dyn. 2011 Apr;240(4):839-49
Assay type: Western blot
MGI Accession ID: MGI:5285231
Gene symbol: Vangl2
Gene name: VANGL planar cell polarity 2
Results
Image: 1D ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
B6:129 +/+ E16.5 (a) TS24: brain Present involves: 129S6/SvEvTac * C57BL/6 Not Specified
Lpm2Jus / Lpm2Jus E16.5 (a) TS24: brain Present (b) involves: 129S6/SvEvTac * C57BL/6J Vangl2ska17/Vangl2ska17Not Specified
A/J:B6 +/+ E16.5 (a) TS24: brain Present involves: A * C57BL/6 Not Specified
Lp / + E16.5 (a) TS24: brain Weak (c) involves: A * C57BL/6 Vangl2Lp/Vangl2+Not Specified
Lp / Lp E16.5 (a) TS24: brain Trace (d) involves: A * C57BL/6 Vangl2Lp/Vangl2LpNot Specified
Notes:
(a) Age of embryo at noon of plug day not specified in reference.
(b) Expression level was 90% as compared to wild-type.
(c) Expression level was reduced by 32% in heterozygotes compared with wild type.
(d) Expression almost completely eliminated in homozygous embryos. Authors report a very faint band detected upon longer autoradiographic exposure.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory