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Gene Expression Data
Assay Details
Assay
Reference: J:170473 Naka T, et al., Spatiotemporal expression of sclerostin in odontoblasts during embryonic mouse tooth morphogenesis. J Endod. 2011 Mar;37(3):340-5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5284874
Gene symbol: Sost
Gene name: sclerostin
Antibody: anti-Sost
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: upper jaw incisor Absent 1A

Specimen 1B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lower jaw incisor Absent 1B

Specimen 1C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: upper jaw molar Absent 1C

Specimen 1D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lower jaw molar Absent 1D

Specimen 1E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: upper jaw incisor Absent 1E

Specimen 1F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw incisor Absent 1F

Specimen 1G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: upper jaw molar Absent 1G

Specimen 1H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw molar Absent 1H
TS22: lower jaw skeleton Present Regionally restricted 1H Expression in osteocytes of the newly formed jaw bone.

Specimen 2A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: upper jaw incisor Present Regionally restricted 2A , 2B Expression in the pre-dentin-secreting odontoblasts.

Specimen 2C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: upper jaw molar Absent 2C

Specimen 2D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lower jaw incisor Present Regionally restricted 2E , 2D Expression in the pre-dentin-secreting odontoblasts.
TS24: lower jaw skeleton Present Regionally restricted 2D Expression in some osteocytes of the newly formed jaw bone.

Specimen 2F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lower jaw molar Absent 2F
TS24: lower jaw skeleton Present Regionally restricted 2F Expression in some osteocytes of the newly formed jaw bone.

Specimen 3A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: upper jaw incisor Present Regionally restricted 3A , 3B Expression in the predentin-secreting odontoblasts.
TS26: upper jaw skeleton Present Regionally restricted 3A Expression in the osteocytes of the jaw bone.

Specimen 3C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: upper jaw molar Absent 3C
TS26: upper jaw skeleton Present Regionally restricted 3C Expression in the osteocytes of the jaw bone.

Specimen 3D: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lower jaw incisor Present Regionally restricted 3D , 3E Expression in the predentin-secreting odontoblasts.
TS26: lower jaw skeleton Present Regionally restricted 3D Expression in the osteocytes of the jaw bone.

Specimen 3F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lower jaw skeleton Present Regionally restricted 3F Expression in the osteocytes of the jaw bone.
TS26: lower jaw molar Absent 3F

Specimen 4A: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: upper jaw incisor Present Regionally restricted 4B , 4A Expression in dentin matrix-secreting odontoblasts.
TS27: upper jaw Present Regionally restricted 4B , 4A Expression in the osteocytes of the jaw bone.

Specimen 4C: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: lower jaw incisor Present Regionally restricted 4C , 4D Expression in dentin matrix-secreting odontoblasts.
TS27: mandible Present Regionally restricted 4C Expression in the osteocytes of the jaw bone.

Specimen 4E: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: lower jaw molar Present Regionally restricted 4F , 4E Expression in pre-dentin-secreting odontoblasts.

Specimen 5A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lower jaw incisor Present Regionally restricted 5A , 5B , 5C Expression in pre-dentin-secreting odontoblasts.
TS28: mandible Present Regionally restricted 5A Expression in the osteocytes of the jaw bone.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory