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Gene Expression Data
Assay Details
Assay
Reference: J:37711 Song WJ, et al., Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome critical region. Genomics. 1996 Dec 15;38(3):331-9
Assay type: RNA in situ
MGI Accession ID: MGI:5141732
Gene symbol: Dyrk1a
Gene name: dual-specificity tyrosine phosphorylation regulated kinase 1a
Probe: Dyrk cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5A: embryonic day 13.0-13.5 (more )
Note: 58-60 pairs of somites.
Structure Level Pattern Image Note
TS21: spinal cord Present 5A
TS21: telencephalon Present 5A
Specimen 5C: embryonic day 15.0-15.5 (more )
Structure Level Pattern Image Note
TS23: telencephalon Present Regionally restricted 5C Expression is in the outer rim.
TS23: olfactory lobe Present 5C
TS23: metencephalon Present Diffuse 5C
TS23: midbrain Present Diffuse 5C
Specimen 5E: embryonic day 17.0-17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex Present 5E
TS25: olfactory lobe Present 5E
Specimen 6A: embryonic day 15.0-15.5 (more )
Structure Level Pattern Image Note
TS23: spinal cord Present 6A
TS23: metencephalon Present Diffuse 6A
TS23: midbrain Present Diffuse 6A
TS23: lung Weak 6A The authors state that signal was not consistent in all of the sections they examined.
TS23: thymus primordium Weak 6A The authors state that signal was not consistent in all of the sections they examined.
Specimen 6C: embryonic day 15.0-15.5 (more )
Structure Level Pattern Image Note
TS23: olfactory lobe Present 6C
Specimen 6E: embryonic day 17.0-17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex Present 6E
TS25: eye Present Regionally restricted 6E Expression is within the sensory layer of the eye.
Specimen Not shown, E13: embryonic day 13.0-13.5 (more )
Structure Level Pattern Image Note
TS21: spinal cord Present
Specimen Not shown, E17: embryonic day 17.0-17.5 (more )
Structure Level Pattern Image Note
TS25: lung Weak The authors state that signal was not consistent in all of the sections they examined.
TS25: thymus Weak The authors state that signal was not consistent in all of the sections they examined.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory