Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(H2-Kb-NFKB2*)808Hfdg
Name:	transgene insertion 808, Han-Fei Ding
MGI ID:	MGI:5141435
Synonyms:	p80HT, p80HT_808
Transgene:	Tg(H2-Kb-NFKB2*)808Hfdg  Location: unknown
Alliance:	Tg(H2-Kb-NFKB2*)808Hfdg page

Strain of Origin:

(C57BL/6J x SJL/J)F2

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(H2-Kb-NFKB2*)808Hfdg expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human NFKB2 (4791) Nfkb2  (MGI:1099800)   Mutation details: The human p80HT coding sequence was amplified by PCR, using a human fetus Marathon-ready cDNA library (Clontech) as the template and specific primers based on the published p80HT sequence (GenBank U09609), and cloned into pHSE3', a vector containing an H-2Kb promoter and an immunoglobulin mu chain enhancer for transgene expression in lymphocytes. Line 808 was generated. (J:123872)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:123872 Zhang B, et al., NF-kappaB2 mutation targets TRAF1 to induce lymphomagenesis. Blood. 2007 Jul 15;110(2):743-51
All:	1 reference(s)