Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slc17a6tm2(cre)Lowl
Name:	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; targeted mutation 2, Bradford B Lowell
MGI ID:	MGI:5141269
Synonyms:	Vglut2Cre, Vglut2-ires-Cre
Gene:	Slc17a6  Location: Chr7:51271754-51320867 bp, + strand  Genetic Position: Chr7, 32.78 cM, cytoband B4
Alliance:	Slc17a6tm2(cre)Lowl page

Germline Transmission:	Earliest citation of germline transmission: J:174691
Parent Cell Line:	W4 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Slc17a6tm2(cre)Lowl expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Slc17a6 (MGI:2156052)   Mutation details: A targeting vector, constructed from a BAC clone containing the Slc17a6 (Vglut2) gene, was utilized to insert an internal ribosomal entry site followed by the cre recombinase sequence into the Slc17a6 locus just downstream of the endogenous stop codon. Cre is expressed from the Slc17a6 gene promoter. (J:174691)

Activity:	Tissue activity of this recombinase allele
Driver:	Slc17a6 (mouse) Summary of all recombinase alleles driven by Slc17a6. Comparative matrix view of recombinase activities Alliance mouse Slc17a6 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Slc17a6 Mutation:	59 strains or lines available

Original:	J:174691 Vong L, et al., Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons. Neuron. 2011 Jul 14;71(1):142-54
All:	379 reference(s)