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Gene Expression Data
Assay Details
Assay
Reference: J:174145 Ningxia Z, et al., The expression pattern of polycomb group protein ezh2 during mouse embryogenesis. Anat Rec (Hoboken). 2011 Jul;294(7):1150-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5141081
Gene symbol: Ezh2
Gene name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Antibody: anti-Ezh2 (AC22; #3147)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen Not shown E6.5: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: embryo Moderate

Specimen 1A: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo ectoderm Present 1A
TS11: extraembryonic mesoderm Present 1A
TS11: extraembryonic visceral endoderm Present 1A
TS11: amnion Absent 1A
TS11: chorion Absent 1A

Specimen Not shown E8.5: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: extraembryonic component Present Regionally restricted Expression is in the visceral endoderm and the extra-embryonic mesoderm.
TS13: embryo ectoderm Present
TS13: amnion Absent
TS13: chorion Absent

Specimen 1B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: somite Moderate 1B

Specimen 2A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: nervous system Strong 2A Expression is in almost all the nerve cells and neuroglial cells, absent in nerve fibers.

Specimen 2B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: myelencephalon Strong 2B

Specimen Not shown E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural tube lateral wall Strong Regionally restricted Expression is in anterior horn neurons.

Specimen 2C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: nervous system Absent 2C Absent in neurons and neuroglial cells.

Specimen 3A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: intestine epithelium Strong 3A

Specimen 3B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: liver Moderate 3B Expression is in most liver and Kupffer cells.

Specimen 3C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: liver Trace 3C

Specimen 3D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: pancreas Strong 3D Expression is in both acinar and tubular epithelial cells, absent in other parts of the pancreas.

Specimen 4A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: renal tubule Present Regionally restricted 4A Expression is in the nuclei of renal tubule epithelial cells.

Specimen 4B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: renal tubule Weak Regionally restricted 4B Expression is in the nuclei of renal tubule epithelial cells.

Specimen 5A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung Strong 5A

Specimen 5B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lobar bronchus Strong Regionally restricted 5B Expression is in parts of pulmonary alveoli and some bronchial branches.

Specimen 5C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lung Absent 5C

Specimen 6A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: heart Weak 6A

Specimen 6B: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: heart Absent 6B Ambiguous: the text and figure indicate expression is absent but the table states that there was weak expression.

Specimen Table 2 E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: nervous system Weak Regionally restricted Expression is in nerve cells and is absent in nerve fiber.
TS17: heart Weak
TS17: liver Weak

Specimen Table 2 E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: nervous system Present Regionally restricted Expression is in nerve cells and is absent in nerve fiber.
TS19: liver Present
TS19: heart Weak
TS19: trachea Absent

Specimen Table 2 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nervous system Strong Regionally restricted Expression is in nerve cells and is absent in nerve fiber.
TS20: lung Strong
TS20: heart Present
TS20: intestine Present
TS20: pancreas Present
TS20: liver Weak
TS20: arterial system Absent
TS20: trachea Absent

Specimen Table 2 E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: nervous system Present Regionally restricted Expression is in nerve cells and is absent in nerve fiber.
TS21: heart Present
TS21: liver Present
TS21: intestine Weak
TS21: lung Weak
TS21: pancreas Weak
TS21: arterial system Absent
TS21: trachea Absent

Specimen Table 2 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nervous system Weak Regionally restricted Expression is in nerve cells and is absent in nerve fiber.
TS22: intestine Weak
TS22: lung Weak
TS22: pancreas Weak
TS22: heart Present
TS22: liver Present
TS22: arterial system Absent
TS22: trachea Absent

Specimen Table 2 E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: nervous system Present Regionally restricted Expression is in nerve cells and is absent in nerve fiber.
TS23: heart Present
TS23: intestine Present
TS23: liver Present
TS23: pancreas Present
TS23: lung Weak
TS23: Bowman's capsule of maturing renal corpuscle Absent
TS23: arterial system Absent
TS23: trachea Absent

Specimen Table 2 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: nervous system Present Regionally restricted Expression is in nerve cells and is absent in nerve fiber.
TS24: heart Present
TS24: liver Present
TS24: intestine mucosa Present
TS24: pancreas Present
TS24: lung Weak
TS24: Bowman's capsule of maturing renal corpuscle Absent
TS24: arterial system Absent
TS24: trachea Absent

Specimen Table 2 E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: intestine mucosa Weak
TS25: liver Weak
TS25: lung Trace
TS25: heart Absent Ambiguous: the text and figure indicate expression is absent but the table states that there was weak expression.
TS25: nervous system Absent Absent to trace in nerve cells and absent in nerve fiber. Ambiguous: the text indicates it is absent but the table shows a that it was either absent to a trace amount in nerve cells.
TS25: Bowman's capsule of mature renal corpuscle Absent
TS25: arterial system Absent
TS25: trachea Absent

Specimen Table 2 E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: heart Trace
TS26: intestine mucosa Trace
TS26: liver Trace
TS26: nervous system Absent Absent to trace in nerve cells and absent in nerve fiber. Ambiguous: the text indicates it is absent but the table shows a that it was either absent to a trace amount in nerve cells.
TS26: lung Absent Ambiguous: the text and figure indicate expression is absent but the table states that there was absent to trace amounts of expression.
TS26: glomerular tuft Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory