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Gene Expression Data
Assay Details
Assay
Reference: J:26846 Shalaby F, et al., Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature. 1995 Jul 6;376(6535):62-6
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5140083
Gene symbol: Kdr
Gene name: kinase insert domain protein receptor
Reporter: lacZ
Direct Detection
Assay notes: Embryos were fixed in a mixture of 0.2% glutaraldehyde and 1.5% formaldhyde before undergoing the color reaction. Post reaction they were fixed in 3.7% formaldehyde.
Results
Specimen 2a: embryonic day 9.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS15: dorsal aorta Present 2a
TS15: endocardial lining Present 2a
TS15: blood vessel Present 2a Expression is present in intersomitic vessels and capillaries.
Specimen 2b: embryonic day 9.5; Kdrtm1Jrt/Kdrtm1Jrt (more )
Structure Level Pattern Image Note
TS15: dorsal aorta Absent 2b
TS15: endocardial lining Absent 2b
TS15: blood vessel Absent 2b There is no expression where the intersomitic vessls and capillaries should be.
Specimen 2c: embryonic day 9.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS15: extraembryonic blood vessel Present Regionally restricted 2c Expression is present in the yolk sac vasculature.
Specimen 2d: embryonic day 9.5; Kdrtm1Jrt/Kdrtm1Jrt (more )
Structure Level Pattern Image Note
TS15: extraembryonic blood vessel Absent 2d There is no expression where the yolk sac vasculature should be.
Specimen 2e: embryonic day 8.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS13: dorsal aorta Present 2e
Specimen 2f: embryonic day 8.5; Kdrtm1Jrt/Kdrtm1Jrt (more )
Structure Level Pattern Image Note
TS13: dorsal aorta Absent 2f
Specimen 2g: embryonic day 7.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS11: blood island Present 2i , 2g
Specimen 2h: embryonic day 7.5; Kdrtm1Jrt/Kdrtm1Jrt (more )
Structure Level Pattern Image Note
TS11: blood island Absent 2h , 2j
Specimen 3a: embryonic day 8.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS13: dorsal aorta Present 3c , 3a
TS13: vitelline artery Present 3c , 3a
TS13: heart Present Regionally restricted 3a , 3c Expression is present in the endocardium.
TS13: blood Present 3c , 3a
TS13: allantois Present Regionally restricted 3c , 3a Expression is present in the base of the allantois.
Specimen 3b: embryonic day 8.5; Kdrtm1Jrt/Kdrtm1Jrt (more )
Structure Level Pattern Image Note
TS13: dorsal aorta Absent 3b , 3d
TS13: vitelline artery Absent 3b , 3d
TS13: heart Absent 3b , 3d There is no expression in the endocardium.
TS13: blood Absent 3b , 3d
TS13: extraembryonic blood vessel Absent 3b , 3d There is no expression where the yolk sac blood vessels should be.
Specimen 3e: embryonic day 8.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS13: dorsal aorta Present 3g , 3e
TS13: heart Present Regionally restricted 3e , 3g Expression is present in the endocardium.
TS13: blood Present 3e , 3g
Specimen 3f: embryonic day 8.5; Kdrtm1Jrt/Kdrtm1Jrt (more )
Structure Level Pattern Image Note
TS13: dorsal aorta Absent 3h , 3f
TS13: heart Absent 3f , 3h There is no expression in the endocardium.
TS13: blood Absent 3f , 3h
TS13: extraembryonic blood vessel Absent 3h , 3f There is no expression where the yolk sac blood vessels should be.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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