Gene Expression Data
Assay Details
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Assay
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Reference:
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J:28700
Dear TN, et al., The Hox11 gene is essential for cell survival during spleen development. Development. 1995 Sep;121(9):2909-15
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5085899
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Gene symbol:
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Tlx1
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Gene name:
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T cell leukemia, homeobox 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
2 +/- 9.5:
embryonic day 9.5; Tlx1tm1Thr/Tlx1 +
(more  )
Specimen
2 +/- 9.5:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1+
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2 +/- 10.5:
embryonic day 10.5; Tlx1tm1Thr/Tlx1 +
(more )
Specimen
2 +/- 10.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1+
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2 +/- 11.5:
embryonic day 11.5; Tlx1tm1Thr/Tlx1 +
(more )
Specimen
2 +/- 11.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1+
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2 -/- 11.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1tm1Thr
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2 +/- 12.5:
embryonic day 12.5; Tlx1tm1Thr/Tlx1 +
(more )
Specimen
2 +/- 12.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1+
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2 -/- 12.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1tm1Thr
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2 +/- 13.5:
embryonic day 13.5; Tlx1tm1Thr/Tlx1 +
(more )
Specimen
2 +/- 13.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1+
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Age:
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embryonic day 13.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2 -/- 13.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1tm1Thr
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Age:
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embryonic day 13.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
3A +/- 11.5:
embryonic day 11.5; Tlx1tm1Thr/Tlx1 +
(more )
Specimen
3A +/- 11.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1+
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
3A -/- 11.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1tm1Thr
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
3A +/- 12.5:
embryonic day 12.5; Tlx1tm1Thr/Tlx1 +
(more )
Specimen
3A +/- 12.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1+
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
3A -/- 12.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1tm1Thr
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
3A +/- * 12.5:
embryonic day 12.5; Tlx1tm1Thr/Tlx1 +
(more )
Specimen
3A +/- * 12.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1+
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
3A -/- * 12.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1tm1Thr
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
3A +/- 13.5:
embryonic day 13.5; Tlx1tm1Thr/Tlx1 +
(more )
Specimen
3A +/- 13.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1+
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Age:
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embryonic day 13.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
3A -/- 13.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1tm1Thr
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Age:
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embryonic day 13.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: dorsal mesogastrium |
Trace |
Regionally restricted |
3A -/- 13.5
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The spleen anlage was no longer anatomically detectable with expression in only a few residual cells.
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Specimen
4B:
embryonic day 18.5; Tlx1tm1Thr/Tlx1 +
(more )
Specimen
4B:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1+
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: spleen |
Present |
Regionally restricted |
4B
,
4D
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Expression in the outer surface of the capsule and trabeculae. No expression in the intracellular components (mainly erythroid precursors at this stage) and the visceral peritoneum.
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Specimen
4C:
embryonic day 18.5; Tlx1tm1Thr/Tlx1 +
(more )
Specimen
4C:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1+
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: spleen |
Present |
Regionally restricted |
4C
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Expression in the outer surface of the capsule and trabeculae.
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Specimen
not shown:
postnatal adult; Tlx1tm1Thr/Tlx1 +
(more )
Specimen
not shown:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * MF1
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Mutant Allele(s):
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Tlx1tm1Thr/Tlx1+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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