Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1Dwir
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Dagmar Wirth
MGI ID:	MGI:5056481
Synonyms:	ROSALUC
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1Dwir page

Germline Transmission:	Earliest citation of germline transmission: J:173806
Parent Cell Line:	IB10/E14IB10 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A construct, which contained (5' to 3') an adenoviral splice acceptor site (SA); a wild-type FRT site, a floxed inverted luciferase cassette; a puromycin N-acetyltransferase (PAC) gene; a non-integrating FRT site; and a promoter and start-codon deficient neomycin phosphotransferase gene, was inserted into the locus. This allele is suitable for RMCE to replace the inverted luciferase gene with a gene of interest. (J:173806)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:173806 Sandhu U, et al., Strict control of transgene expression in a mouse model for sensitive biological applications based on RMCE compatible ES cells. Nucleic Acids Res. 2011 Jan 1;39(1):e1
All:	1 reference(s)