Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(S100B)#Daoh
Name:	transgene insertion, Alexander Marks
MGI ID:	MGI:5052145
Transgene:	Tg(S100B)#Daoh  Location: unknown
Alliance:	Tg(S100B)#Daoh page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(S100B)#Daoh expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human S100B (6285) S100b  (MGI:98217)   Mutation details: A 17.3 kb fragment of human genomic DNA containing the S100B gene and its transcriptional control elements was used as the transgene. Expression of the human gene in transgenic animals was verified by Northern and Western blot analysis. Strong expression of the transgene was detected in the brain, and very low levels expression was detected in the liver, heart, and kidney. Multiple lines were created this record is for unidentified lines. (J:78970)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:131137 Borella A, et al., Characterization of social behaviors and oxytocinergic neurons in the S-100 beta overexpressing mouse model of Down Syndrome. Behav Brain Res. 2003 May 15;141(2):229-36
All:	8 reference(s)