Tg(S100B)8Daoh
Transgene Detail
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Symbol: |
Tg(S100B)8Daoh |
Name: |
transgene insertion 8, Alexander Marks |
MGI ID: |
MGI:5052141 |
Transgene: |
Tg(S100B)8Daoh Location: unknown
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Alliance: |
Tg(S100B)8Daoh page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(S100B)8Daoh expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
S100B (6285) |
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Mutation details: A 17.3 kb fragment of human genomic DNA containing the S100B gene and its transcriptional control elements was used as the transgene. Expression of the human gene in transgenic animals was verified by Northern and Western blot analysis. Strong expression of the transgene was detected in the brain, and very low levels expression was detected in the liver, heart, and kidney. This line carries approximately 70 copies of the transgene.
(J:78970)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:78970 Friend WC, et al., Cell-specific expression of high levels of human S100 beta in transgenic mouse brain is dependent on gene dosage. J Neurosci. 1992 Nov;12(11):4337-46 |
All: |
9 reference(s) |
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