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Tg(S100B)8Daoh
Transgene Detail
Summary
Symbol: Tg(S100B)8Daoh
Name: transgene insertion 8, Alexander Marks
MGI ID: MGI:5052141
Transgene: Tg(S100B)8Daoh  Location: unknown  
Alliance: Tg(S100B)8Daoh page
Transgene
origin
Strain of Origin:  CD-1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(S100B)8Daoh expresses 1 gene
 
Mutation detailsA 17.3 kb fragment of human genomic DNA containing the S100B gene and its transcriptional control elements was used as the transgene. Expression of the human gene in transgenic animals was verified by Northern and Western blot analysis. Strong expression of the transgene was detected in the brain, and very low levels expression was detected in the liver, heart, and kidney. This line carries approximately 70 copies of the transgene. (J:78970)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:78970 Friend WC, et al., Cell-specific expression of high levels of human S100 beta in transgenic mouse brain is dependent on gene dosage. J Neurosci. 1992 Nov;12(11):4337-46
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory