Gene Expression Data
Assay Details
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Assay
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Reference:
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J:50488
ten Berge D, et al., Prx1 and Prx2 in skeletogenesis: roles in the craniofacial region, inner ear and limbs. Development. 1998 Oct;125(19):3831-42
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5050657
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Gene symbol:
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Prrx2
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Gene name:
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paired related homeobox 2
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
6A:
embryonic day 12.5; Prrx2tm1Hubr/Prrx2 +
(more  )
Note: Tissue was embedded in hydroxyethylmethacrylate polymer.
Specimen
6A:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd * FVB
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Mutant Allele(s):
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Prrx2tm1Hubr/Prrx2+
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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2% Paraformaldehyde
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Embedding:
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Resin/plastic
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Note:
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Tissue was embedded in hydroxyethylmethacrylate polymer.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: mandibular process |
Present |
Regionally restricted |
6A
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Expression was found medially in the distal part of the mandible underneath the incisor buds and surrounding the mesenchymal condensations of the distal tip of Meckel's cartilage.
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Specimen
6B:
embryonic day 12.5; Prrx2tm1Hubr/Prrx2 +
(more )
Note: Tissue was embedded in hydroxyethylmethacrylate polymer.
Specimen
6B:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * FVB
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Mutant Allele(s):
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Prrx2tm1Hubr/Prrx2+
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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2% Paraformaldehyde
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Embedding:
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Resin/plastic
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Note:
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Tissue was embedded in hydroxyethylmethacrylate polymer.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: mandibular process |
Present |
Regionally restricted |
6B
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Expression was concentrated underneath the dental lamina, in a domain abutting Meckel's cartilage dorsally, and laterally from Meckel's cartilage in condensed mesenchyme, presumably the progenitor of the dentary.
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Specimen
6C:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * FVB
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Mutant Allele(s):
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Prrx2tm1Hubr/Prrx2+
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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2% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
6D:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB
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Mutant Allele(s):
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Prrx1tm1Tex/Prrx1tm1Tex
Prrx2tm1Hubr/Prrx2tm1Hubr
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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2% Paraformaldehyde
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Embedding:
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Resin/plastic
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Note:
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Tissue was embedded in hydroxyethylmethacrylate polymer.
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Specimen
6E:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * FVB
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Mutant Allele(s):
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Prrx2tm1Hubr/Prrx2+
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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2% Paraformaldehyde
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Specimen
10F:
embryonic day 11.5; Prrx2tm1Hubr/Prrx2 +
(more )
Note: Tissue was embedded in hydroxyethylmethacrylate polymer.
Specimen
10F:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * FVB
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Mutant Allele(s):
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Prrx2tm1Hubr/Prrx2+
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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2% Paraformaldehyde
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Embedding:
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Resin/plastic
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Note:
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Tissue was embedded in hydroxyethylmethacrylate polymer.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: inner ear |
Present |
Regionally restricted |
10F
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Expression is dorsoanteriorly on the diverticulum of the lateral duct, on the anterior side of the diverticulum of the posterior duct and on the anterior side of the anterior duct.
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| TS19: head mesenchyme |
Strong |
Regionally restricted |
10F
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Expression is in the mesenchyme surrounding the lateral side of the otocyst and around the outgrowing diverticula.
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Specimen
not shown:
embryonic day 8.5; Prrx2tm1Hubr/Prrx2 +
(more )
Specimen
not shown:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * FVB
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Mutant Allele(s):
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Prrx2tm1Hubr/Prrx2+
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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Specimen
not shown:
embryonic day 9.5; Prrx2tm1Hubr/Prrx2 +
(more )
Specimen
not shown:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * FVB
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Mutant Allele(s):
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Prrx2tm1Hubr/Prrx2+
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: head mesenchyme |
Present |
Regionally restricted |
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Expression in the region near the otocyst where the future ossicles will develop.
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Specimen
not shown:
embryonic day 10.5; Prrx2tm1Hubr/Prrx2 +
(more )
Specimen
not shown:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * FVB
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Mutant Allele(s):
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Prrx2tm1Hubr/Prrx2+
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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Specimen
not shown:
embryonic day 11.5; Prrx2tm1Hubr/Prrx2 +
(more )
Specimen
not shown:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * FVB
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Mutant Allele(s):
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Prrx2tm1Hubr/Prrx2+
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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Specimen
not shown:
embryonic day 12.5; Prrx2tm1Hubr/Prrx2 +
(more )
Specimen
not shown:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * FVB
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Mutant Allele(s):
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Prrx2tm1Hubr/Prrx2+
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: inner ear |
Present |
Regionally restricted |
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Expression is dorsoanteriorly on the diverticulum of the lateral duct, on the anterior side of the diverticulum of the posterior duct and on the anterior side of the anterior duct.
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| TS20: head mesenchyme |
Present |
Regionally restricted |
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Expression is in the mesenchyme surrounding the lateral side of the otocyst and around the outgrowing diverticula.
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| TS20: head |
Weak |
Regionally restricted |
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Faint expression in the second arch.
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