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Tg(Krt5-Ctnnb1*)#Gluk
Transgene Detail
Summary
Symbol: Tg(Krt5-Ctnnb1*)#Gluk
Name: transgene insertion, Marina A Glukhova
MGI ID: MGI:5049918
Synonyms: K5-deltaN57-betacat
Transgene: Tg(Krt5-Ctnnb1*)#Gluk  Location: unknown  
Alliance: Tg(Krt5-Ctnnb1*)#Gluk page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Krt5-Ctnnb1*)#Gluk expresses 1 gene
 
Mutation detailsA modified mouse beta-catenin that lacks sequence for amino acids 1-57 was hemagglutinin tagged and placed under the control of the keratin 5 promoter. Two transgenic lines (7, and 33) are discussed. Between 10 and 20 copies of the transgene were inserted. (J:95360)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:95360 Teuliere J, et al., Targeted activation of {beta}-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia. Development. 2005 Jan;132(2):267-277
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory