Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Slc6a3-icre/ERT2)2Gloss
Name:	transgene insertion 2, Bernd Gloss
MGI ID:	MGI:5049906
Synonyms:	DAT-iCreER
Transgene:	Tg(Slc6a3-icre/ERT2)2Gloss  Location: unknown
Alliance:	Tg(Slc6a3-icre/ERT2)2Gloss page

Strain of Origin:

C57BL/6NTac

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Slc6a3-icre/ERT2)2Gloss expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Slc6a3 (MGI:94862)   Mutation details: The mouse bacterial artificial chromosome (BAC) RP23-408F13 containing Slc6a3, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, gene, was modified by insertion of sequence encoding iCreER at the Slc6a3 translation initiation ATG, and addition of a Kozak sequence upstream of the ATG. This BAC also contains the following genes: Clptm1l (CLPTM1-like), Tert (telomerase reverse transcriptase), and Slc6a18 (solute carrier family 6 (neurotransmitter transporter), member 18). The modified BAC was used to generate the DAT-iCreER transgene, which was microinjected into C57BL/6NTac fertilized eggs. Founder line 2 was subsequently established. (J:173676)

Activity:	Tissue activity of this recombinase allele
Driver:	Slc6a3 (mouse) Summary of all recombinase alleles driven by Slc6a3. Alliance mouse Slc6a3 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:173676 Gloss B, Generation of an inducible Slc6a3 cre transgene. MGI Direct Data Submission. 2011;
All:	7 reference(s)