Ascl3 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:139151 Bullard T, et al., Ascl3 expression marks a progenitor population of both acinar and ductal cells in mouse salivary glands. Dev Biol. 2008 Aug 1;320(1):72-8
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:5014320
Gene symbol:	Ascl3
Gene name:	achaete-scute family bHLH transcription factor 3

Reporter:	Cre
Antibody:	anti-cre (Covance)
Detection system:	Secondary antibody coupled to Cy3

Results

2C ©

Specimen 2C: postnatal; Ascl3^{tm1(EGFP/cre)Ovi}/Ascl3⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: submandibular gland	Present	Regionally restricted	2C	No expression is observed in acinar cells.

Specimen not shown: postnatal; Ascl3^{tm1(EGFP/cre)Ovi}/Ascl3⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: parotid gland	Present	Regionally restricted		Expression is present in duct, but not acinar cells.

6D ©

Specimen 6D: postnatal month 5; Ascl3^{tm1(EGFP/cre)Ovi}/Ascl3⁺, Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ (more

)
Note: Conditional mutant. Double labeled: red - Ascl3; green - Aqp5 (assay MGI:5051833).

Structure	Level	Pattern	Image	Note
TS28: sublingual gland	Present	Regionally restricted	6D	Expression is present in the duct, but not acinar, cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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