Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Nppa-cre)m-3+4Vmc
Name:	transgene insertion m-3+4, Vincent M Christoffels
MGI ID:	MGI:5013828
Synonyms:	-3/+4mCre, NppaCre+
Transgene:	Tg(Nppa-cre)m-3+4Vmc  Location: unknown
Alliance:	Tg(Nppa-cre)m-3+4Vmc page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Nppa-cre)m-3+4Vmc expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Nppa (MGI:97367)   Mutation details: The transgenic construct consists of a sequence fragment encoding a consensus Kozak signal, a nuclear localization signal and cre recombinase inserted at the start codon of the mouse Nppa genomic sequence (-3 to +4 kb relative to the transcription start site). The 0.7 kb proximal regulatory region, containing the promoter and silencer and enhancer sequences, is included, as is the NRSE (neuron-restrictive silencer element) in the 3' UTR. (J:86158)

Activity:	Tissue activity of this recombinase allele
Driver:	Nppa (mouse) Summary of all recombinase alleles driven by Nppa. Alliance mouse Nppa gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

21 assay results 1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:86158 de Lange FJ, et al., Atrial cardiomyocyte-specific expression of Cre recombinase driven by an Nppa gene fragment. Genesis. 2003 Sep;37(1):1-4
All:	8 reference(s)