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Gene Expression Data
Assay Details
Assay
Reference: J:12699 Della NG, et al., Isolation and characterisation of murine homologues of the Drosophila seven in absentia gene (sina). Development. 1993 Apr;117(4):1333-43
Assay type: RNA in situ
MGI Accession ID: MGI:5013449
Gene symbol: Siah2
Gene name: siah E3 ubiquitin protein ligase 2
Probe: Siah-2 cDNA2
Probe preparation: Antisense RNA
Visualized with: Autoradiography
Assay notes: The length of the probe was reduced to 100-200 bases by alkaline hydrolysis. Probes were either labeled with 32-P or 35-S.
Results
Specimen 5A-C,E,F,H,I: embryonic day 17.5 (more )
Note: (A,B,E and H) Bright-field illumination. A is a low power view, B,E, and H are magnified areas of the boxed regions in (A). (C,F, I) Dark-field illumination of the sections B,E, and H.
Structure Level Pattern Image Note
TS25: retina Present 5B/C , 5A
TS25: retina nuclear layer Strong Regionally restricted 5B/C , 5A Expression is in the ganglion cell layer.
TS25: olfactory epithelium Present 5A , 5E/F
TS25: nasal cavity respiratory epithelium Absent 5E/F , 5A
TS25: cartilage Present Regionally restricted 5A , 5H/I Expression is in cells of proliferating cartilage but not in hypertrophied chondrocytes.
TS25: cranium Present Regionally restricted 5A Expression is in areas of proliferating cartilage at the base of the skull.
TS25: temporo-mandibular joint Present Regionally restricted 5A Expression is in areas of proliferating cartilage.
TS25: vertebra Present Regionally restricted 5A Expression is in areas of proliferating cartilage.

Specimen Not shown: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: forebrain Present
TS25: gonad Present

Specimen 6B/C: embryonic day 10.5 (more )
Note: Shown are a low power view and high power views of a brightfield/darkfield pair of the same section.
Structure Level Pattern Image Note
TS17: olfactory placode Absent 6B/C

Specimen 6F/G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: olfactory epithelium Absent 6F/G

Specimen 6J/K: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: olfactory epithelium Present 6J/K

Specimen 6N/O: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: olfactory epithelium Present 6N/O

Specimen 6R/S: postnatal week 2 (more )
Structure Level Pattern Image Note
TS28: olfactory epithelium Strong 6R/S

Specimen Not shown: postnatal week 2 (more )
Structure Level Pattern Image Note
TS28: forebrain Weak
TS28: retina Weak


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory