Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Clec16acurt
Name:	C-type lectin domain family 16, member A; curvy tail
MGI ID:	MGI:5009280
Gene:	Clec16a  Location: Chr16:10363203-10562742 bp, + strand  Genetic Position: Chr16, 5.68 cM
Alliance:	Clec16acurt page

Strain of Origin:

SWR/J-Clcn1adr-mto/J

Allele Type:    Spontaneous Mutation:    Intragenic deletion   Mutation details: This spontaneous mutation presents as a 4 base pair deletion in exon 21 at chromosome 16 position 10,694,632-635 bp (GRCm38), which results in a frameshift mutation that leads to the introduction of novel amino acids and an early termination codon. Transcript levels of this mutant allele were found to be significantly decreased in homozygous embryonic fibroblasts. (J:190968, J:222308, J:251104) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Clec16a Mutation:	48 strains or lines available

Original:	J:172931 Harris BS, et al., Curvy tail: a new skeletal mutation that maps to Chromosome 16. MGI Direct Data Submission. 2011;
All:	4 reference(s)