Summary | Transgene origin | Transgene description | Recombinase activity | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(Sox9-cre/ERT2)1Msan
Name:	transgene insertion 1, Maike Sander
MGI ID:	MGI:5009223
Synonyms:	Sox9CreER, Sox9CreERT2
Transgene:	Tg(Sox9-cre/ERT2)1Msan  Location: unknown
Alliance:	Tg(Sox9-cre/ERT2)1Msan page

Strain of Origin:

(BALB/c x C57BL/6)F2

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Sox9-cre/ERT2)1Msan expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Sox9 (MGI:98371)   Mutation details: BAC RP23-229L12 was modified by inserting a Kozak-cre/ERT2-polyA in place of the ATG codon in exon 1 of the Sox9 open reading frame. The purified construct was injected into the pronuclei of fertilized CB6F2 oocytes. (J:170126)

Activity:	Tissue activity of this recombinase allele
Driver:	Sox9 (mouse) Summary of all recombinase alleles driven by Sox9. Comparative matrix view of recombinase activities Alliance mouse Sox9 gene page

List all tumor models in MMHCdb carrying Tg(Sox9-cre/ERT2)1Msan

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:170126 Kopp JL, et al., Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas. Development. 2011 Feb;138(4):653-65
All:	58 reference(s)