Tg(Thy1-APPSwDutLon)101Lpr
Transgene Detail
|
Symbol: |
Tg(Thy1-APPSwDutLon)101Lpr |
Name: |
transgene insertion 101, Laurent Pradier |
MGI ID: |
MGI:5003456 |
Synonyms: |
Thy1-APP751 |
Transgene: |
Tg(Thy1-APPSwDutLon)101Lpr Location: unknown
|
Alliance: |
Tg(Thy1-APPSwDutLon)101Lpr page
|
|
Strain of Origin: |
CBA x C57BL/6
|
|
Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
Mutation: |
|
Insertion
|
|
|
Tg(Thy1-APPSwDutLon)101Lpr expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
APP (351) |
|
|
|
|
|
Mutation details: The murine Thy1 promoter drives expression of a human APP cDNA bearing 3 mutations Swedish (S: KM595/596NL), Dutch (D:E618Q), and London (L: V6421). This line has very low levels of transgene expression.
(J:86694)
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
Original: |
J:86694 Blanchard V, et al., Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice. Exp Neurol. 2003 Nov;184(1):247-63 |
All: |
5 reference(s) |
|