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Tg(Thy1-APPSwDutLon)101Lpr
Transgene Detail
Summary
Symbol: Tg(Thy1-APPSwDutLon)101Lpr
Name: transgene insertion 101, Laurent Pradier
MGI ID: MGI:5003456
Synonyms: Thy1-APP751
Transgene: Tg(Thy1-APPSwDutLon)101Lpr  Location: unknown  
Alliance: Tg(Thy1-APPSwDutLon)101Lpr page
Transgene
origin
Strain of Origin:  CBA x C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Thy1-APPSwDutLon)101Lpr expresses 1 gene
 
Mutation detailsThe murine Thy1 promoter drives expression of a human APP cDNA bearing 3 mutations Swedish (S: KM595/596NL), Dutch (D:E618Q), and London (L: V6421). This line has very low levels of transgene expression. (J:86694)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:86694 Blanchard V, et al., Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice. Exp Neurol. 2003 Nov;184(1):247-63
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory