Tg(CD21,CD35)38Bhub
Transgene Detail
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| Symbol: |
Tg(CD21,CD35)38Bhub |
| Name: |
transgene insertion 38, Brigitte T Huber |
| MGI ID: |
MGI:5002652 |
| Synonyms: |
CR2/CD21 transgenic |
| Transgene: |
Tg(CD21,CD35)38Bhub Location: unknown
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| Alliance: |
Tg(CD21,CD35)38Bhub page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CD21,CD35)38Bhub expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
CR2 (1380) |
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Mutation details: A BAC, RP11-35C1, that contains human CD21 and complement receptor 1 (CD35) genes was used to generate transgenic mice. The BAC contains the native human regulatory elements and promoters for CR2 expression. In addition to line 38, lines 18 and 36 were also generated, with line 38 exhibiting the highest expression levels.
(J:138376)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:138376 Hsiao FC, et al., Cutting edge: Epstein-Barr virus transactivates the HERV-K18 superantigen by docking to the human complement receptor 2 (CD21) on primary B cells. J Immunol. 2006 Aug 15;177(4):2056-60 |
| All: |
3 reference(s) |
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Analysis Tools
