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Fgfbp3tm1Tohe
Targeted Allele Detail
Summary
Symbol: Fgfbp3tm1Tohe
Name: fibroblast growth factor binding protein 3; targeted mutation 1, Toshio Heike
MGI ID: MGI:4949899
Synonyms: fgf-bp3lacZ
Gene: Fgfbp3  Location: Chr19:36894950-36896999 bp, - strand  Genetic Position: Chr19, 32.01 cM
Alliance: Fgfbp3tm1Tohe page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171305
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA lacZ and neo cassette replaced the coding region in exon 2. The absence of transcript expression is confirmed by RT-PCR analysis on brain extracts. (J:171305)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgfbp3 Mutation:  18 strains or lines available
References
Original:  J:171305 Yamanaka Y, et al., Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors. Mol Cell Neurosci. 2011 Jan;46(1):200-12
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory