Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Resp18tm1Mlit
Name:	regulated endocrine-specific protein 18; targeted mutation 1, Jian Fei
MGI ID:	MGI:4949626
Gene:	Resp18  Location: Chr1:75248843-75255059 bp, - strand  Genetic Position: Chr1, 38.65 cM
Alliance:	Resp18tm1Mlit page

Germline Transmission:	Earliest citation of germline transmission: J:171182
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The open reading frame was replaced by a neo cassette. A 50% reduction in protein expression was confirmed by western blot analysis on heterozygous brain extracts. (J:171182)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Resp18 Mutation:	17 strains or lines available

Original:	J:171182 Liang M, et al., Requirement of regulated endocrine-specific protein-18 for development and expression of regulated endocrine-specific protein-18 isoform c in mice. Mol Biol Rep. 2011 Apr;38(4):2557-62
All:	2 reference(s)