Tg(Thy1-spH)64Vnmu
Transgene Detail
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| Symbol: |
Tg(Thy1-spH)64Vnmu |
| Name: |
transgene insertion 64, Venkatesh N Murthy |
| MGI ID: |
MGI:4949114 |
| Synonyms: |
spH64 |
| Transgene: |
Tg(Thy1-spH)64Vnmu Location: unknown
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| Alliance: |
Tg(Thy1-spH)64Vnmu page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Thy1-spH)64Vnmu expresses
1 gene
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Mutation details: The transgenic construct contains spH, the pH-sensitive variant of the green fluorescent protein (ecliptic pHluorin) fused to the mouse synaptic vesicle-associated membrane protein 2 (Vamp2), under the control of the mouse thymus cell antigen 1 (Thy1) promoter. In founder line spH64, transgene expression is detected in GABAergic or inhibitory neurons of the hippocampus. Synaptic activity, as determined by fluorescence, is detectable starting at approximately postnatal day 10 in cultured hippocampal glutamatergic neurons.
(J:98425)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:98425 Li Z, et al., Synaptic vesicle recycling studied in transgenic mice expressing synaptopHluorin. Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6131-6 |
| All: |
2 reference(s) |
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Analysis Tools
