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Gene Expression Data
Assay Details
Assay
Reference: J:105464 Amrein L, et al., Expression patterns of nm23 genes during mouse organogenesis. Cell Tissue Res. 2005 Dec;322(3):365-78
Assay type: RNA in situ
MGI Accession ID: MGI:4949064
Gene symbol: Nme1
Gene name: NME/NM23 nucleoside diphosphate kinase 1
Probe: nm23-M1 i
Probe preparation: labelled with S35
Visualized with: Autoradiography
Assay notes: Two oligonucleotide probes were described for this gene (see probe records MGI:4948915 and MGI:4948916 for the sequences). Authors indicate that one or both were used in this RNA in situ hybridization assay.
Results
Specimen 3a: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: nervous system Present 3a
TS21: dorsal root ganglion Strong 3a

Specimen Table 1 E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebellum Strong
TS21: cerebral cortex Strong
TS21: dorsal root ganglion Strong
TS21: midbrain Strong
TS21: spinal cord Strong
TS21: trigeminal ganglion Strong
TS21: heart Moderate
TS21: thymus primordium Moderate
TS21: tongue Moderate
TS21: intestine Weak
TS21: lung Weak

Specimen Table 1 E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: main olfactory bulb Present Regionally restricted Expression was abundant in the granular cell layer but low in the subependymal zone.
TS23: cerebellum Strong
TS23: cerebral cortex ventricular layer Strong
TS23: cortical plate Strong
TS23: dorsal root ganglion Strong
TS23: eye Strong
TS23: heart Strong
TS23: midbrain Strong
TS23: spinal cord Strong
TS23: trigeminal ganglion Strong
TS23: hair follicle Moderate
TS23: tongue Moderate
TS23: intestine Weak
TS23: lung Weak
TS23: thymus primordium Weak

Specimen Table 1 E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: main olfactory bulb Present Regionally restricted Expression was abundant in the granular cell layer but low in the subependymal zone.
TS26: cerebellum Present Regionally restricted Expression was low in the external granular layer but abundant in the internal granular layer.
TS26: cortical plate Strong
TS26: dorsal root ganglion Strong
TS26: eye Strong
TS26: midbrain Strong
TS26: thymus Strong
TS26: trigeminal ganglion Strong
TS26: hair follicle Moderate
TS26: spinal cord Moderate
TS26: tongue Moderate
TS26: cerebral cortex ventricular zone Weak
TS26: heart Weak
TS26: intestine Weak
TS26: lung Weak

Specimen 4a/b: embryonic day 18.5 (more )
Note: Fig. 4a - darkfield, 4b brightfield.
Structure Level Pattern Image Note
TS26: main olfactory bulb Present Regionally restricted 4a , 4b Expression was detected in the differentiating cells of the granule cell layer of the olfactory bulbs but was weak in the subependymal zone.

Specimen 5a: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cortical plate Present 5a

Specimen 6a: embryonic day 18.5 (more )
Note: Double labeled with BrdU (brown).
Structure Level Pattern Image Note
TS26: cortical plate Present Regionally restricted 6a Expression was detected in non-proliferating cells of the cortical plate.

Specimen 6b: embryonic day 18.5 (more )
Note: Double labeled with BrdU (brown).
Structure Level Pattern Image Note
TS26: cortical plate Present Regionally restricted 6b Expression was detected in non-proliferating cells of the cortical plate.

Specimen 6c: embryonic day 18.5 (more )
Note: Double labeled with BrdU (brown).
Structure Level Pattern Image Note
TS26: cortical plate Present Regionally restricted 6c Expression was detected in non-proliferating cells of the cortical plate.

Specimen 7a: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebellum Present Regionally restricted 7a Preferentially expressed in the internal granule cell layer.

Specimen 8a: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present Regionally restricted 8a All differentiating neurons were labeled.

Specimen 8b: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: dorsal root ganglion Present Regionally restricted 8b All differentiating neurons were labeled.

Specimen 8c: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present Regionally restricted 8c All differentiating neurons were labeled.

Specimen 10a: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: heart Present 10a Maximum expression in the heart was reached at E15.5.

Specimen 10b: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: heart Present 10b Expression decreased at E18.5 heart compared to E15.5.

Specimen 11a: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: thymus primordium Present 11a

Specimen 11b: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: thymus Present 11b Expression in the thymus increased between E15.5 and E18.5.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory