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Tg(WT1)HNdh
Transgene Detail
Summary
Symbol: Tg(WT1)HNdh
Name: transgene insertion H, Nicholas D Hastie
MGI ID: MGI:2183705
Synonyms: Wt1-LacZ, WT470LZH, yWT470LacZ
Transgene: Tg(WT1)HNdh  Location: unknown  
Alliance: Tg(WT1)HNdh page
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA 470 kb YAC containing the entire human WT1 gene with an in frame fusion of a lacZ reporter to exon 1 was used as the transgene. (J:52222)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Founder H carries 9 tandem copies of the transgene integrated near the telomere of chromosome 4. Expression of the transgene is strong and the expression pattern is similar to that of endogenous murine Wt1.
References
Original:  J:52222 Moore AW, et al., YAC transgenic analysis reveals Wilms' tumour 1 gene activity in the proliferating coelomic epithelium, developing diaphragm and limb. Mech Dev. 1998 Dec;79(1-2):169-84
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory