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Gene Expression Data
Assay Details
Assay
Reference: J:104961 St Germain C, et al., Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development. Mol Reprod Dev. 2005 Dec;72(4):483-93
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4947707
Gene symbol: Pcsk1
Gene name: proprotein convertase subtilisin/kexin type 1
Antibody: anti-PC1-CT
Detection system: Secondary antibody coupled to Alexa Fluor 594
Assay notes: The antibody used in this assay only recognizes the isoforms of the protein which contain the C-terminus.
Results
Specimen 3Aa: postnatal (more )
Note: Unfertilized egg.
Structure Level Pattern Image Note
TS28: oocyte Present Uniform 3Aa There is even staining in the cytoplasm.
Specimen 3Ab: embryonic day 0.5 (more )
Note: 1 cell embryo.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Non-Uniform 3Ab Expression is primarily in the pronuclei.
Specimen 3Ac: embryonic day 0.5 (more )
Note: 1 cell embryo.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Non-Uniform 3Ac Expression is primarily in the pronuclei.
Specimen 3Ad: embryonic day 1.0 (more )
Note: 2 cell embryo.
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 3Ad Expression is present throughout the cytoplasm.
Specimen 3Ae: embryonic day 2.5 (more )
Note: 6-8 cell embryo.
Structure Level Pattern Image Note
TS3: 4-8 cell stage embryo Present Non-Uniform 3Ae Expression is perinucleur and punctated.
Specimen 3Af: embryonic day 3.0 (more )
Note: Morula.
Structure Level Pattern Image Note
TS4: compacted morula Present Non-Uniform 3Af Expression is most intense at blastomere junctions.
Specimen 3Ag: embryonic day 3.5 (more )
Note: Blastocyst.
Structure Level Pattern Image Note
TS4: blastocyst Present Non-Uniform 3Ag Expression is most intense at blastomere junctions.
Specimen 4A: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: blastocyst Present 4Aa , 4Ac Expression is present in the cytoplasm.
Specimen 4B: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: blastocyst Present 4Bc , 4Ba Expression is generally non-nuclear or perinuclear.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory