Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Et(icre)23031Rdav
Name:	enhancer trap 23031, Ron Davis
MGI ID:	MGI:4947559
Transgene:	Et(icre)23031Rdav  Location: unknown
Alliance:	Et(icre)23031Rdav page

Strain of Origin:	C57BL/6J
Project Collection:	Neuroscience Blueprint cre

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Et(icre)23031Rdav expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Et(icre)23031Rdav (MGI:4947597)   Mutation details: An enhancer trap transgenic approach was used to generate these mice. The Calb1-icre transgene was designed with a 300 bp minimal promoter from the mouse calbindin 1 locus, a codon-improved cre recombinase (icre; improved with mammalian codon usage, no putative cryptic splice sites, altered stop codon, and reduced CpG content to limit the chances of epigenetic silencing in mammals), and an SV40 late polyA signal. This transgene was injected into C57BL/6J mouse embryos. Founders were crossed to C57BL/6 animals. Animals were crossed to B6-Gt(ROSA)26Sortm1Sor mice to assess cre activity/transmission. Cre positive, lacZ negative mice were subsequently bred to C57BL/6 mice to create the 23031 line. (J:150856)

Activity:	Tissue activity of this recombinase allele
Driver:	Et(icre)23031Rdav (mouse) Summary of all recombinase alleles driven by Et(icre)23031Rdav. Alliance mouse Et(icre)23031Rdav gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:150856 Davis R, Large-scale enhancer trap project to generate transgenic cre alleles by Ron Davis at Baylor University. MGI Direct Data Submission. 2009;
All:	1 reference(s)