Tg(MMTV-SRC*Y527F)2Mul
Transgene Detail
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| Symbol: |
Tg(MMTV-SRC*Y527F)2Mul |
| Name: |
transgene insertion 2, William Muller |
| MGI ID: |
MGI:4947369 |
| Synonyms: |
MMTV-c-srcAct |
| Transgene: |
Tg(MMTV-SRC*Y527F)2Mul Location: unknown
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| Alliance: |
Tg(MMTV-SRC*Y527F)2Mul page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(MMTV-SRC*Y527F)2Mul expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| chicken |
SRC (396442) |
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Mutation details: Chicken SRC sequence, mutated so that codon 527 encodes phenylalanine rather than tyrosine, was placed under the control of the murine mammary tumor virus long terminal repeat promoter. Seven potential founders were produced but only four generated offspring. Lines 2 and 5 have been described. Line 2 is the representative.
(J:56331)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:56331 Webster MA, et al., Induction of mammary epithelial hyperplasias and mammary tumors in transgenic mice expressing a murine mammary tumor virus/activated c-src fusion gene. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7849-53 |
| All: |
2 reference(s) |
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Analysis Tools
