About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:139718 Hatch EP, et al., Fgf16(IRESCre) mice: a tool to inactivate genes expressed in inner ear cristae and spiral prominence epithelium. Dev Dyn. 2009 Feb;238(2):358-66
Assay type: RNA in situ
MGI Accession ID: MGI:4943676
Gene symbol: Fgf16
Gene name: fibroblast growth factor 16
Probe: Fgf16 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A/S1 A: embryonic day 9.0 (more )
Note: This specimen has 14 somites.
Structure Level Pattern Image Note
TS14: otic pit Weak Regionally restricted 1A There is weak expression in the posterior otic cup.
TS14: branchial arch endoderm Present Regionally restricted S1_A Expression is present in the posterior pharyngeal pouch endoderm.
Specimen 1A': embryonic day 9.0 (more )
Note: This specimen has 14 somites.
Structure Level Pattern Image Note
TS14: otic pit Weak Regionally restricted 1A' There is weak expression in the posterior otic cup.
Specimen S1 A': embryonic day 9.0 (more )
Note: This specimen has 14 somites.
Structure Level Pattern Image Note
TS14: branchial arch endoderm Present Regionally restricted S1_A' Expression is present in the posterior pharyngeal pouch endoderm.
Specimen S1 A'': embryonic day 9.0 (more )
Note: This specimen has 14 somites.
Structure Level Pattern Image Note
TS14: olfactory placode Present S1_A''
Specimen 1B/S1 B: embryonic day 9.0 (more )
Note: This specimen has 17 somites.
Structure Level Pattern Image Note
TS14: otic pit Present Regionally restricted 1B Expression, stronger than that seen at the 14 somite stage, is localized to the posterior otic cup.
TS14: branchial arch endoderm Present Regionally restricted S1_B Expression is present in the posterior pharyngeal pouch endoderm.
Specimen 1B': embryonic day 9.0 (more )
Note: This specimen has 17 somites.
Structure Level Pattern Image Note
TS14: otic pit Present Regionally restricted 1B' Expression, stronger than that seen at the 14 somite stage, is localized to the posterior otic cup.
Specimen S1 B': embryonic day 9.0 (more )
Note: This specimen has 17 somites.
Structure Level Pattern Image Note
TS14: branchial arch endoderm Present Regionally restricted S1_B' Expression is present in the posterior pharyngeal pouch endoderm.
Specimen S1 B'': embryonic day 9.0 (more )
Note: This specimen has 17 somites.
Structure Level Pattern Image Note
TS14: olfactory placode Present S1_B''
Specimen Not shown: embryonic day 9.5 (more )
Note: This specimen has 21 somites.
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted Expression is present in the posterior otic vesicle, marking the dorsolateral region.
Specimen 1C/S1 C: embryonic day 9.5 (more )
Note: This specimen has 23 somites.
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted 1C Expression is present in the posterior otic vesicle, marking the dorsolateral region.
TS15: branchial arch endoderm Present Regionally restricted S1_C Expression is present in the posterior pharyngeal pouch endoderm.
Specimen 1C': embryonic day 9.5 (more )
Note: This specimen has 23 somites.
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted 1C' Expression is present in the posterior otic vesicle, marking the dorsolateral region.
Specimen S1 C': embryonic day 9.5 (more )
Note: This specimen has 23 somites.
Structure Level Pattern Image Note
TS15: branchial arch endoderm Present Regionally restricted S1_C' Expression is present in the posterior pharyngeal pouch endoderm.
Specimen S1 C'': embryonic day 9.5 (more )
Note: This specimen has 23 somites.
Structure Level Pattern Image Note
TS15: olfactory placode Present S1_C''
Specimen 1D: embryonic day 10.0 (more )
Note: This specimen has 28 somites.
Structure Level Pattern Image Note
TS16: otocyst Present Regionally restricted 1D Expression is restricted to a posterolateral domain, located midway between the dorsal and ventral poles of the vesicle.
Specimen 1D': embryonic day 10.0 (more )
Note: This specimen has 28 somites.
Structure Level Pattern Image Note
TS16: otocyst Present Regionally restricted 1D' Expression is restricted to a posterolateral domain, located midway between the dorsal and ventral poles of the vesicle.
Specimen 1E: embryonic day 10.0 (more )
Note: This specimen has 30 somites.
Structure Level Pattern Image Note
TS16: otocyst Present Regionally restricted 1E Expression is restricted to a posterolateral domain, located midway between the dorsal and ventral poles of the vesicle.
Specimen 1E': embryonic day 10.0 (more )
Note: This specimen has 30 somites.
Structure Level Pattern Image Note
TS16: otocyst Present Regionally restricted 1E' Expression is restricted to a posterolateral domain, located midway between the dorsal and ventral poles of the vesicle.
Specimen 1F: embryonic day 11.0 (more )
Note: This specimen has 40 somites.
Structure Level Pattern Image Note
TS18: otocyst Present Regionally restricted 1F Expression is found in two spots in the developing cristae--the anterior/lateral cristae and the posterior crista.
Specimen 1G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: superior semicircular canal Present Regionally restricted 1G Expression is present in the developing anterior crista (as well as the other developing cristae) but not in other regions of the developing semicircular canal ducts.
Specimen 1H: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: posterior semicircular canal Present Regionally restricted 1H Expression is present in the developing lateral and posterior cristae (as well as the developing anterior crista) but not in other regions of the developing semicircular canal ducts.
Specimen 1I: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: saccule Present Regionally restricted 1I Expression is present in several cells at the lateral (non-sensory) edge of the cochlear duct; levels are higher at the apex than the base of the duct.
Specimen 1J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: saccule Present Regionally restricted 1J Expression is present in several cells at the lateral (non-sensory) edge of the cochlear duct; levels are higher at the apex than the base of the duct.
Specimen 1K: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: saccule Present Regionally restricted 1K Expression is present in several cells at the lateral (non-sensory) edge of the cochlear duct; levels are higher at the apex than the base of the duct.
Specimen 1L: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: superior semicircular canal Present Regionally restricted 1L' , 1L Expression is present in the developing cristae (such as the anterior crista).
TS21: semicircular canal Weak Regionally restricted 1L' , 1L Weak expression is present in patches of presumptive non-sensory epithelium of the semicircular canal adjacent to the cristae.
Specimen 1M: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: saccule Absent 1M
TS21: utricle Absent 1M
Specimen 1N: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: posterior semicircular canal Present Regionally restricted 1N Expression is present in the developing cristae (such as the posterior crista).
TS21: cochlear duct Present Single cells 1N , 1N' Expression is present in a few cells of the lateral wall of the cochlear duct.
Specimen 1O: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: superior semicircular canal Present Regionally restricted 1O , 1O' Expression is present in the cristae (such as the anterior crista). There is also expression in the thin canal wall opposite the cristae.
Specimen 1P: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lateral semicircular canal Present Regionally restricted 1P Expression is present in the cristae (such as the anterior crista).
Specimen 1Q: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlear duct Present Regionally restricted 1Q , 1Q' Expression is present in the lateral cochlear duct.
Specimen 1R: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: posterior semicircular canal Weak Regionally restricted 1R , 1R' Although markedly reduced relative to earlier stages, expression is still present in the cristae (such as the posterior crista).
TS24: cochlear duct Strong Regionally restricted 1R'' , 1R Expresson is present in the lateral cochlear duct.
Specimen 1S: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: posterior semicircular canal Weak Regionally restricted 1S Although markedly reduced relative to earlier stages, expression is still present in the cristae (such as the posterior crista).
Specimen 1T: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cochlear duct Strong Regionally restricted 1T Expresson is present in the lateral cochlear duct.
Specimen S1 D: embryonic day 9.5 (more )
Note: This specimen has 27 somites.
Structure Level Pattern Image Note
TS15: branchial arch endoderm Present Regionally restricted S1_D Expression is present in the posterior pharyngeal pouch endoderm.
Specimen S1 D': embryonic day 9.5 (more )
Note: This specimen has 27 somites.
Structure Level Pattern Image Note
TS15: branchial arch endoderm Present Regionally restricted S1_D' Expression is present in the posterior pharyngeal pouch endoderm.
Specimen S1 D'': embryonic day 9.5 (more )
Note: This specimen has 27 somites.
Structure Level Pattern Image Note
TS15: olfactory placode Present S1_D''
Specimen S1 E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future adenohypophysis Present S1_E Expression is present in the anterior pituitary.
Specimen S1 E': embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: olfactory epithelium Present S1_E'
Specimen S1 F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: adenohypophysis Present S1_F Expression is present in the anterior pituitary.
Specimen S1 F': embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: olfactory epithelium Present S1_F'
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory