Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Shroom3m1Nisw
Name:	shroom family member 3; mutation 1, Lee Niswander
MGI ID:	MGI:4943186
Gene:	Shroom3  Location: Chr5:92831294-93113177 bp, + strand  Genetic Position: Chr5, 47.29 cM, cytoband E3
Alliance:	Shroom3m1Nisw page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Nucleotide substitutions   Mutation details: Following multidose N-ethyl-N-nitrosourea (ENU) treatments to induce mutations in founder C57BL/6J mice, a forward genetic screen was utilized to identify mice exhibiting defects in the closure of embryonic fissures (including the neural tube, body wall, and face). A single nucleotide polymorphism (SNP) was found, resulting in a C to T transition. This caused an arginine to cysteine change in exon 9. (J:169831)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Shroom3 Mutation:	204 strains or lines available

Original:	J:169831 Niswander L, Direct Data Submission 2011/03/29. MGI Direct Data Submission. 2011;
All:	4 reference(s)