Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sla2tm1Amch
Name:	Src-like-adaptor 2; targeted mutation 1, Alec M Cheng
MGI ID:	MGI:4941869
Gene:	Sla2  Location: Chr2:156716071-156729161 bp, - strand  Genetic Position: Chr2, 77.89 cM
Alliance:	Sla2tm1Amch page

Germline Transmission:	Earliest citation of germline transmission: J:169170
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 2, 3, and 4 were replaced with a puro cassette. The absence of protein expression was confirmed by western blot analysis on splenocytes and thymocytes. (J:169170)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sla2 Mutation:	25 strains or lines available

Original:	J:169170 Liontos LM, et al., The Src-like adaptor protein regulates GM-CSFR signaling and monocytic dendritic cell maturation. J Immunol. 2011 Feb 15;186(4):1923-33
All:	2 reference(s)