Summary | Mutation origin | Mutation description | Find Mice (IMSR) | Notes | References

Symbol:	Itpr3tm1.1Rmnc
Name:	inositol 1,4,5-triphosphate receptor 3; targeted mutation 1.1, Rocky Mountain Regional Neurological Disorders Center
MGI ID:	MGI:4941855
Synonyms:	IP3R3tm1(tauGFP), Itpr3tm1.1(Mapt/GFP)Rmnc
Gene:	Itpr3  Location: Chr17:27276278-27341197 bp, + strand  Genetic Position: Chr17, 13.68 cM
Alliance:	Itpr3tm1.1Rmnc page

Germline Transmission:	Earliest citation of germline transmission: J:169498
Parent Cell Line:	EC7.1 (ES Cell)
Strain of Origin:	(C57BL/6J x 129X1/SvJ)F1

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1 was replaced with a MAPT/GFP fusion, 3 polyadenylation sequences, and a floxed neo cassette. Cre-mediated recombination removed the neo cassette. (J:169498)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Itpr3 Mutation:	174 strains or lines available

Original:	J:169498 Hegg CC, et al., Microvillous cells expressing IP3 receptor type 3 in the olfactory epithelium of mice. Eur J Neurosci. 2010 Nov;32(10):1632-45
All:	5 reference(s)