Kncn Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:97933 Leibovici M, et al., Initial characterization of kinocilin, a protein of the hair cell kinocilium. Hear Res. 2005 May;203(1-2):144-53
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:4939651
Gene symbol:	Kncn
Gene name:	kinocilin

Antibody:	16GC antibody
Detection system:	Secondary antibody

Results

Specimen 2A: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: semicircular duct ampulla	Strong	Regionally restricted	2A	Expression is in kinocilia.

Specimen 3A: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: inner ear vestibular component	Present	Regionally restricted	3A	Expression is in the growing kinocilium of the vestibular hair cells.

Specimen 3B: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: cochlear duct epithelium	Present	Regionally restricted	3B	Expression is in kinocilia of outer and inner hair cells.

Specimen 3C: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: organ of Corti	Present	Regionally restricted	3C	Expression is in kinocilia.

Specimen 3E: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: organ of Corti	Present	Regionally restricted	3E	Expression is in a belt-like shape around the cuticular plate and at the position of the basal body in hair cells.

Specimen 4: postnatal (more

)

Structure	Level	Pattern	Image	Note
TS28: organ of Corti	Present	Regionally restricted	4

Specimen 5A,B,C: postnatal adult (more

)
Note: Optical sections in (A), (B) and (C) are identical.

Structure	Level	Pattern	Image	Note
TS28: cochlear duct	Present	Regionally restricted	5C , 5A , 5B	Kinocilin localizes close to the base of stereocilia in sensory cochlear cells.

Specimen 5D: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: cochlear duct	Present	Regionally restricted	5D	Kinocilin localizes close to the base of stereocilia in sensory cochlear cells.

Specimen 6A: postnatal (more

)

Structure	Level	Pattern	Image	Note
TS28: seminiferous tubule epithelium	Present	Regionally restricted	6A	Expression is comma-shaped in cells.

Specimen 6D,E: postnatal (more

)
Note: (E) Enlargement of (D)

Structure	Level	Pattern	Image	Note
TS28: spermatid	Present	Regionally restricted	6D , 6E	Expression is localized to the manchette of the elongating spermatid.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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