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Tg(Trpv5-EGFP)1Prae
Transgene Detail
Summary
Symbol: Tg(Trpv5-EGFP)1Prae
Name: transgene insertion 1, Jeppe Praetorius
MGI ID: MGI:4888742
Synonyms: TRPV5-EGFP
Transgene: Tg(Trpv5-EGFP)1Prae  Location: unknown  
Alliance: Tg(Trpv5-EGFP)1Prae page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F2
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA 3.6 KB fragment of the Trpv5 promoter was used to drive expression of EGFP in this construct. The vector was microinjected into male pronuclei of B6D2F2 zygotes. Seven founders were generated. A line that showed high EGFP expression in renal late distal convoluted tubules (DCT2s), connecting tubules (CNTs), and the initial part of the cortical collecting duct (iCCD) was chosen for further analysis. (A second a low-expressing line displaying mosaic expression in the tubules was also analyzed.) (J:168534)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:168534 Hofmeister MV, et al., The TRPV5 Promoter as a Tool for Generation of Transgenic Mouse Models. Adv Exp Med Biol. 2011;704:277-86
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory