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Tg(Tex101-icre)2Lzj
Transgene Detail
Summary
Symbol: Tg(Tex101-icre)2Lzj
Name: transgene insertion 2, Zi-Jian Lan
MGI ID: MGI:4888565
Synonyms: Tex101-iCre
Transgene: Tg(Tex101-icre)2Lzj  Location: unknown  
Alliance: Tg(Tex101-icre)2Lzj page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Tex101-icre)2Lzj expression driven by 1 gene
 
Mutation detailsA construct in which the Tex101 promoter fragment was cloned in front of a codon-improved cre cassette with the nuclear localization signal from the SV40 large T antigen and the SV40 polyadenylation signal was microinjected in (C57BL/6 x SJL)F2 fertilized eggs. 3 lines were produced and crossed to ROSA26 reporter mice. In two lines (#1 and #5), ectopic activity was detected (all tested tissues stained), but reporter staining in crosses derived from #2 was robust in the testis with no staining in ovary or other tissues. (Spotty staining on the kidney surface was observed). Line 2 was analyzed in further detail. (J:168353)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tex101 (species not specified)
Summary of all recombinase alleles driven by Tex101.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:168353 Lei Z, et al., Postnatal male germ-cell expression of cre recombinase in Tex101-iCre transgenic mice. Genesis. 2010 Dec;48(12):717-22
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory