Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Thy1-spH)21Vnmu
Name:	transgene insertion 21, Venkatesh N Murthy
MGI ID:	MGI:4882125
Synonyms:	spH21
Transgene:	Tg(Thy1-spH)21Vnmu  Location: unknown
Alliance:	Tg(Thy1-spH)21Vnmu page

Strain of Origin:

(C57BL/6 x CBA)F1

Transgene Type:    Transgenic (Reporter) Mutation:    Insertion   Mutation details: The transgenic construct contains spH, the pH-sensitive variant of the green fluorescent protein (ecliptic pHluorin) fused to the mouse synaptic vesicle-associated membrane protein 2 (Vamp2), under the control of the mouse thymus cell antigen 1 (Thy1) promoter. In founder line spH21, transgene expression is detected in glutamatergic or excitatory neurons of the hippocampus. Synaptic activity, as determined by fluorescence, is detectable starting at approximately postnatal day 10 in cultured hippocampal glutamatergic neurons. (J:98425)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:98425 Li Z, et al., Synaptic vesicle recycling studied in transgenic mice expressing synaptopHluorin. Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6131-6
All:	2 reference(s)