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Tg(Ddx4-cre/ERT2)1Dcas
Transgene Detail
Summary
Symbol: Tg(Ddx4-cre/ERT2)1Dcas
Name: transgene insertion 1, Diego H Castrillon
MGI ID: MGI:4882088
Synonyms: Vasa-Cre, Vasa-CreERT2
Transgene: Tg(Ddx4-cre/ERT2)1Dcas  Location: unknown  
Alliance: Tg(Ddx4-cre/ERT2)1Dcas page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Tg(Ddx4-cre/ERT2)1Dcas expression driven by 1 gene
 
Mutation detailsThe transgene construct consists of the Ddx4 (Vasa) promoter driving the expression of a cre/ERT2 cassette. The purified construct was injected into FVB/N oocytes. Transgenic animals were produced with one line showing high expression in the testis and ovary, but not in any somatic tissues, was selected for further analysis. (J:138697)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ddx4 (species not specified)
Summary of all recombinase alleles driven by Ddx4.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:138697 John GB, et al., Foxo3 is a PI3K-dependent molecular switch controlling the initiation of oocyte growth. Dev Biol. 2008 Sep 1;321(1):197-204
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory