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Del(4Ago3-Ago4)1Ghan
Targeted Allele Detail
Summary
Symbol: Del(4Ago3-Ago4)1Ghan
Name: deletion, Chr 4, Gregory J Hannon 1
MGI ID: MGI:4881450
Synonyms: Ago3/1/4def, Del1Ghan, Del(Eif2c3/Eif2c1/Eif2c4)1Ghan
Gene: Del(4Ago3-Ago4)1Ghan  Location: unknown  Genetic Position: Chr4, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Intergenic deletion, Intragenic deletion
  Del(4Ago3-Ago4)1Ghan involves 4 genes/genome features (Gm22033, Ago3, Ago1 ...) View all
 
Mutation detailsUsing the MICER gene targeting system, 5'Hprt and 3'Hprt vectors containing exons from either side of the targeted region, single loxP sites, and a neomycin or puromycin drug selection cassette were used to flank the region. Cre-mediated recombination removed Eif2c3, Eif2c1, and Eif2c4. (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Del(4Ago3-Ago4)1Ghan Mutation:  1 strain or line available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory