Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ripply3tm1Sjt
Name:	ripply transcriptional repressor 3; targeted mutation 1, Shinji Takada
MGI ID:	MGI:4880754
Gene:	Ripply3  Location: Chr16:94129281-94137794 bp, + strand  Genetic Position: Chr16, 55.17 cM, cytoband C4
Alliance:	Ripply3tm1Sjt page

Germline Transmission:	Earliest citation of germline transmission: J:167713
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 1 - 3 were replaced with an IRES-lacZ-pgk-neo cassette via homologous recombination. RT-PCR analysis confirmed the absence of expression in homozygous embryos at E9.5. (J:167713)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	17 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ripply3 Mutation:	9 strains or lines available

Original:	J:167713 Okubo T, et al., Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice. Development. 2011 Jan;138(2):339-48
All:	5 reference(s)