Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rr10tm1.1Kubo
Name:	regulatory region 10; targeted mutation 1.1, Masato Kubo
MGI ID:	MGI:4880752
Gene:	Rr10  Location: unknown  Genetic Position: Chr11, Syntenic
Alliance:	Rr10tm1.1Kubo page

Germline Transmission:	Earliest citation of germline transmission: J:167446
Parent Cell Line:	M1/M-1 (ES Cell)
Strain of Origin:	(129 x C57BL/6)F1

Allele Type:    Targeted (Modified regulatory region, Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The HS4 enhancer element downstream of the Il4 3'UTR was replaced with a floxed neomycin resistance gene cassette that was subsequently removed by cre-mediated recombination. (J:167446)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr10 Mutation:	0 strains or lines available

Original:	J:167446 Tanaka S, et al., The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells. Nat Immunol. 2011 Jan;12(1):77-85
All:	2 reference(s)